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Prolonged activated partial thromboplastin time with no clear explanation
Blood Coagulation & Fibrinolysis, 2020Evaluation of bleeding risk before operation includes history of bleeding, complete blood count and basic coagulation tests, prothrombin time and activated partial thromboplatin time (aPTT).
Sigal, Nakav +4 more
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Comparison of Several Activated Partial Thromboplastin Time Methods
American Journal of Clinical Pathology, 1975Activated partial thromboplastin times (APTT's) performed with a semi-automated electrical-conductivity type of clot timer on plasmas from patients with hepatic disease and intravascular coagulation, and on warfarin or heparin therapy, were significantly lower than when done on the same plasmas with either a manual optical method or an automated ...
R J, Morin, D, Willoughby
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Kaolin-correctable Prolongation of the Activated Partial Thromboplastin Time
American Journal of Clinical Pathology, 1980Seven patients who had normal prothrombin times but prolonged activated partial thromboplastin times (aPTT) are described. The prolonged aPTT, obtained with micronized silica as the contact activating agent in a semi-automated optical end-point system, a nonautomated optical end-point system, and a conductivity end-point system, corrected to normal ...
M F, Briselli, L, Ellman
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Shortened activated partial thromboplastin time: causes and management
Blood Coagulation & Fibrinolysis, 2010Throughout the long history of the hemostasis laboratory, and as an evaluation of the coagulation cascade, the results of the activated partial thromboplastin time (APTT) have primarily been considered as an index of loss-of-function and rarely as an index of gain-of-function.
LIPPI, Giuseppe +4 more
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Extremely Shortened Activated Partial Thromboplastin Times
JAMA: The Journal of the American Medical Association, 1980To the Editor.— The presence of a hypercoagulable state in patients with a shortened activated partial thromboplastin time (APTT) as manifested by the clinical association with an increased incidence of thromboembolic disease has previously been reported by Hume, 1 Gallus et al, 2 Pilgeram, 3 McKenna et al, 4 and McKenna et al.
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Bleeding in Patients With Activated Partial Thromboplastin Time Inhibitors
Southern Medical Journal, 1982We present a case in which an activated partial thromboplastin time (aPTT) inhibitor may have significantly contributed to prolonged bleeding in a patient and review five similar cases. The possibility of an aPTT inhibitor should be considered in the evaluation of patients with unexplained prolongation of PTT and PT.
S B, Kalish +3 more
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A laboratory evaluation into the short activated partial thromboplastin time
Blood Coagulation & Fibrinolysis, 2010Although short activated partial thromboplastin times (APTTs) are generally considered to be laboratory artefacts of problematic blood collections, there is mounting evidence that in some cases a short APTT may reflect a hypercoagulable state, potentially associated with increased thrombotic risk and adverse cardiovascular events.
Ashraf, Mina +3 more
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Heparin Monitoring in Sheep by Activated Partial Thromboplastin Time
Artificial Organs, 2003Abstract: Heparin anticoagulation is utilized during and after vascular surgery in animals to reduce the risk of acute or chronic thromboembolic problems. In this study, we examined variation of activated partial thromboplastin time APTT) after the intravenous bolus IV bolus) and subcutaneous SC) heparin injection in order to monitor heparin therapy in
Seok Gon, Park +6 more
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The activated partial thromboplastin time (APTT)
1992The term partial thromboplastin is used to distinguish the reagent from that used in the prothrombin time, since the APTT reagent lacks the apoprotein component of the complete tissue thromboplastin. The APTT is the main test for screening for intrinsic clotting defects including haemophilia. It is also used for detection of lupus anticoagulant and for
L. Poller, J. M. Thomson
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The Activated Partial Thromboplastin Time in the Control of Heparin Treatment
Australasian Annals of Medicine, 1970SummaryThe effect of heparin on the activated partial thromboplastin time and whole blood clotting time was measured in 30 patients with thrombo‐embolic disease. In 27 of these patients there was good correlation between the results of the two tests. Three patients showed little change of the activated partial thromboplastin time, although the clotting
J, Hirsh +3 more
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