Results 21 to 30 of about 16,184,590 (268)

Canine reference intervals for coagulation markers using the STA Satellite and the STA-R Evolution analyzers [PDF]

, 2010
The aim of the current study was to determine canine reference intervals for prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen, and antithrombin (AT) according to international recommendations. The STA Satellite coefficients
Hanot, Camille, Geffré, Anne, Trumel, Catherine, François Vergez, Jean-Pierre Braun, Camille Hanot, Sophie Grollier, Braun, Jean-Pierre, Anne Geffré, Grollier, Sophie, Vergez, François, Catherine Trumel   +11 more
core   +1 more source

Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy

Hepatology, EarlyView., 2022
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann, Marti Cabanes‐Creus, Moritz Ertelt, Renina Gale Navarro, Julie Lucifora, Qinggong Yuan, Karin Nien‐Huber, Ahmed Abdelrahman, Xuan‐Khang Vu, Liang Zhang, Ann‐Christin Franke, Christian Schmithals, Albrecht Piiper, Annabelle Vogt, Maria Gonzalez‐Carmona, Jochen T. Frueh, Evelyn Ullrich, Philip Meuleman, Steven R. Talbot, Margarete Odenthal, Michael Ott, Erhard Seifried, Clara T. Schoeder, Joachim Schwäble, Leszek Lisowski, Hildegard Büning   +25 more
wiley   +1 more source

Aromatic Amines Exert Contrasting Effects on the Anticoagulant Effect of Acetaldehyde upon APTT

Advances in Hematology, 2014
The pharmacological effects of amphetamine, procaine, procainamide, DOPA, isoproterenol, and atenolol upon activated partial thromboplastin time in the absence and presence of acetaldehyde have been investigated.
La'Teese Hall, Sarah J. Murrey, Arthur S. Brecher   +2 more
doaj   +1 more source

Association of coagulation profile with microvascular complications and glycemic control in type 2 diabetes mellitus – a study at a tertiary care center in Delhi

Hematology, Transfusion and Cell Therapy, 2019
Introduction: Type 2 diabetes mellitus, characterized by insulin resistance, corresponds to approximately 90% of cases of diabetes worldwide. Hyperglycemia in diabetes contributes to hyperfibrinogenemia and activates the coagulation cascade thereby ...
Charu Agarwal, Kashish Bansal, Mukta Pujani, Kanika Singh, Varsha Chauhan, Deepshikha Rana, Shveta Lukhmana   +6 more
doaj   +1 more source

Prothrombine and activated partial thromboplastin time are prolonged in hepatic cirrhosis

Universa Medicina, 2016
Background Chronic hepatitis and hepatic cirrhosis are chronic liver diseases that cause disorders of liver function, such as the formation of platelets and coagulation factors (prothrombin time/PT and activated partial thromboplastin time/APTT ...
Edward Kurnia Setiawan Limijadi, Lisyani Budi Suromo, Imam Budiwiyono   +2 more
doaj   +1 more source

The role of hemostatic changes in the pathogenesis of diabetic retinopathy

Journal of Education, Health and Sport, 2022
Introduction: The paper presents the results of the hemostasis system of rats with experimental diabetic retinopathy. Material and methods: Experimental studies were performed on white Wistar rats, which were divided into 2 groups: 1st group – intact
Nataliya Preys, Ivan Savytskyi
doaj   +1 more source

An Evaluation of the Activated Partial Thromboplastin Time Waveform [PDF]

Clinical and Applied Thrombosis/Hemostasis, 2017
The activated partial thromboplastin time (APTT) waveform includes several parameters that are related to various underlying diseases. The APTT waveform was examined in various diseases. Regarding the pattern of APTT waveform, a biphasic pattern of the first or second derivative curve (DC) was observed in patients with hemophilia and patients positive ...
Takeshi, Matsumoto, Hideo, Wada, Naoki, Fujimoto, Junki, Toyoda, Yasunori, Abe, Kohshi, Ohishi, Yoshiki, Yamashita, Makoto, Ikejiri, Kei, Hasegawa, Kei, Suzuki, Hiroshi, Imai, Kaname, Nakatani, Naoyuki, Katayama   +12 more
openaire   +2 more sources

Risk for excessive anticoagulation during hemodialysis is associated with type of vascular access and bedside coagulation testing: Results of a cross-sectional study

Frontiers in Medicine, 2022
BackgroundRecommendations and practice patterns for heparin dosing during hemodialysis show substantial heterogeneity and are scantly supported by evidence.
Marijke De Troyer, Karl Martin Wissing, Dieter De Clerck, Marie-Laure Cambier, Tom Robberechts, Annelies Tonnelier, Karlien François   +6 more
doaj   +1 more source

PENGARUH PENDIAMAN DARAH SITRAT PADA SUHU 2-8°C TERHADAP NILAI ACTIVATED PARTIAL THROMBOPLASTIN TIME (APTT) [PDF]

, 2022
Latar Belakang: Pemeriksaan APTT (Activated Partial Thromboplastin Time) adalah pemeriksaan rutin hemostasis yang digunakan untuk mengevaluasi mekanisme pembekuan darah pasien pada jalur instrinsik dan jalur bersama.
Afifah, Destine
core  

Unexpected, isolated activated partial thromboplastin time prolongation:A practical mini-review

, 2020
A common inquiry in coagulation laboratories is how to interpret an unexpected, isolated prolonged activated partial thromboplastin time (APTT). In this context, isolated means together with a normal prothrombin time (PT) and/or normal international ...
Goetze, Jens Peter, Jens Peter Goetze, Malou Philips, Rasmussen, Katrine Laura, Katrine Laura Rasmussen, Philips, Malou, Armando Tripodi, Tripodi, Armando   +7 more
core   +1 more source