Results 111 to 120 of about 7,192,603 (344)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

MKK3 Mitogen-Activated Protein Kinase Pathway Mediates Carbon Monoxide-Induced Protection Against Oxidant-Induced Lung Injury [PDF]

, 2003
Leo E. Otterbein, Sherrie L. Otterbein, Emeka Ifedigbo, Fang Liu, Danielle Morse, Colleen Fearns, Richard J. Ulevitch, R. G. Knickelbein, Richard A. Flavell, Augustine M.K. Choi   +9 more
openalex   +1 more source

Macrophage activation and polarization: nomenclature and experimental guidelines.

Immunity, 2014
P. Murray, J. Allen, S. Biswas, E. Fisher, D. Gilroy, S. Goerdt, S. Gordon, J. Hamilton, L. Ivashkiv, T. Lawrence, M. Locati, A. Mantovani, F. Martínez, J. Mege, D. Mosser, G. Natoli, J. Saeij, J. Schultze, K. Shirey, A. Sica, J. Suttles, I. Udalova, J. V. Van Ginderachter, S. Vogel, T. Wynn   +24 more
semanticscholar   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

NLRP3 inflammasome activation and cell death

Cellular & Molecular Immunology, 2021
Yi Huang, Wenjing Xu, Rongbin Zhou
semanticscholar   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Impact of Pumice Substitution on Mortar Properties: A Case Study on Mechanical Performance and XRD Analysis

Infrastructures
The incorporation of sustainable construction is essential for minimizing the environmental footprint of cementitious composites. This research examines the mechanical behavior and microstructural features of alternative mortars in which pumice acts as a
Pablo Julián López-Gonzalez, Rodrigo Vivar-Ocampo, Humberto Raymundo González-Moreno, Oscar Moreno-Vazquez, Efrén Meza-Ruíz, Sergio Aurelio Zamora-Castro, David Reyes-González, Joaquin Sangabriel-Lomeli   +7 more
doaj   +1 more source

Exploring the full spectrum of macrophage activation

Nature reviews. Immunology, 2008
D. Mosser, J. Edwards
semanticscholar   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Mycn Is Essential for Pubertal Mammary Gland Development and Promotes the Activation of Bcl11b-Maintained Quiescent Stem Cells

Cells
This investigation examines the function of the mouse Mycn gene in regulating and activating quiescent mammary stem cells, which are vital for mammary gland development. The mammary gland, consisting of luminal and basal cells, progresses through complex
Zuobao Lin, Chunhui Wang, Huiru Bai, Yue Zhang, Meizhen Lin, Xiaoqin Liu, Tian’en Hu, Yuan Meng   +7 more
doaj   +1 more source