Results 141 to 150 of about 2,442,763 (316)

Membrane changes in murine macrophages after in-vivo stimulation and activation

open access: yes, 1983
The expression of various receptors and other surface determinants on resident, glycogen-and Corynebacterium parvum- elicited mouse peritoneal macrophages has been described.
GLASS, EJ, WEIR, DM, STEWART, J
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Influence of activation function in deep learning for cutaneous melanoma identification

open access: yesJournal of Computer Sciences Institute
Malignant melanoma is an aggressive skin cancer requiring early detection for effective treatment. In this study, it is hypothesized that the choice of activation function affects the classification performance of pre-trained models in melanoma ...
Adrian Szymczyk   +1 more
doaj   +1 more source

Molecular determinants of complexin clamping and activation function. [PDF]

open access: yesElife, 2022
Bera M   +4 more
europepmc   +1 more source

Mining Generalizable Activation Functions

open access: yesCoRR
The choice of activation function is an active area of research, with different proposals aimed at improving optimization, while maintaining expressivity. Additionally, the activation function can significantly alter the implicit inductive bias of the architecture, controlling its non-linear behavior. In this paper, in line with previous work, we argue
Alex Vitvitskyi   +5 more
openaire   +2 more sources

Diagram of activation function.

open access: yes, 2019
Diagram of activation function.
Hongliang Fu (582225)   +4 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Universal activation function for machine learning. [PDF]

open access: yesSci Rep, 2021
Yuen B, Hoang MT, Dong X, Lu T.
europepmc   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

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