Results 161 to 170 of about 17,207,076 (361)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Unbalanced protocol recognition method based on improved residual U-Net

网络与信息安全学报
An unbalanced protocol recognition method based on the improved Residual U-Net was proposed to solve the challenge of network security posed by the increasing network attacks with the continuous development of the Internet.In the captured network traffic,
Jisheng WU, Zheng HONG, Tiantian MA
doaj   +1 more source

Activation function 1 of progesterone receptor is required for progesterone antagonism of oestrogen action in the uterus. [PDF]

BMC Biol, 2022
Lee SH, Lim CL, Shen W, Tan SMX, Woo ARE, Yap YHY, Sian CAS, Goh WWB, Yu WP, Li L, Lin VCL.   +10 more
europepmc   +1 more source

Respiration and functional activity [PDF]

The Journal of Physiology, 1936
W, Deutsch, H S, Raper
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Application of an Improved Graph Neural Network for Drug Property Prediction

IEEE Access
The prediction of drug properties plays a vital role in drug research. However, the drug property prediction accuracy of traditional methods is limited due to their inability to fully capture molecular structure and function information. As a result, the
Xiaopu Ma, Zhan Wang, He Li
doaj   +1 more source

CroReLU: Cross-Crossing Space-Based Visual Activation Function for Lung Cancer Pathology Image Recognition. [PDF]

Cancers (Basel), 2022
Liu Y, Wang H, Song K, Sun M, Shao Y, Xue S, Li L, Li Y, Cai H, Jiao Y, Sun N, Liu M, Zhang T.   +12 more
europepmc   +1 more source

Cauchy activation function and XNet

Neural Networks
We have developed a novel activation function, named the Cauchy Activation Function. This function is derived from the Cauchy Integral Theorem in complex analysis and is specifically tailored for problems requiring high precision. This innovation has led to the creation of a new class of neural networks, which we call (Comple)XNet, or simply XNet.
Li, Xin, Xia, Zhihong, Zhang, Hongkun
openaire   +3 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Functionally Active Intrathoracic Neuroblastoma [PDF]

Archives of Disease in Childhood, 1961
R A, Smith, T P, Whitehead, L, Morris, H P, Williams   +3 more
openaire   +2 more sources