Results 121 to 130 of about 341,650 (296)

Diffusion-induced spontaneous pattern formation on gelation surfaces

, 2006
Although the pattern formation on polymer gels has been considered as a result of the mechanical instability due to the volume phase transition, we found a macroscopic surface pattern formation not caused by the mechanical instability.
Chrambach A., de Gennes P.-G., H Katsuragi, Meakin P., Onuki A., Turing A. M., Walgraef D.   +6 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

A normal form for excitable media

, 2006
We present a normal form for travelling waves in one-dimensional excitable media in form of a differential delay equation. The normal form is built around the well-known saddle-node bifurcation generically present in excitable media.
Georg A. Gottwald, Keener J., Lorenz Kramer, Winfree A. T., Zykov V. S.   +4 more
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Breathing Current Domains in Globally Coupled Electrochemical Systems: A Comparison with a Semiconductor Model

, 2001
Spatio-temporal bifurcations and complex dynamics in globally coupled intrinsically bistable electrochemical systems with an S-shaped current-voltage characteristic under galvanostatic control are studied theoretically on a one-dimensional domain.
A. Alekseev, A. DeWit, A. Wacker, A. Wacker, A. Wacker, A.C. Hindmarsh, A.M. Turing, A.V. Gorbatyuk, B. Glavin, B.S. Kerner, C. Canuto, D. Battogtokh, D. Lima, D.P. Valette, D.V. Mel’nikov, E. Schöll, E. Schöll, E. Schöll, F. Mertens, F. Mertens, F. Plenge, F.G. Bass, F.J. Elmer, G. Dewel, G. Flätgen, G. Heidemann, G. Veser, H. Hempel, H. Willebrand, I. Kiss, J. Annamalai, J. Boissonade, J. Christoph, J. Christoph, K. Krischer, K. Krischer, K. Krischer, K. Krischer, K. Rose, K.H. Seung, L. Schimansky-Geier, M. Falcke, M. Falcke, M. Meixner, M. Meixner, M. Meixner, M.D. Graham, M.T.M. Koper, M.T.M. Koper, N. Mazouz, N. Mazouz, N. Mazouz, N. Mazouz, P. Grauel, P. Grauel, P. Rodin, P. Strasser, R.D. Otterstedt, S. Bose, S. Bose, S.A. Zhukov, Sh. M. Kogan, U. Middya, U. Middya, V. Barelko, V.K. Vanag, Y.-J. Li, Y.P. Raizer   +67 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

An instability criterion for activator–inhibitor systems in a two-dimensional ball

Journal of Differential Equations, 2006
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling. [PDF]

, 2015
Matriptase is an epithelia-specific membrane-anchored serine protease that has received considerable attention in recent years because of its consistent dysregulation in human epithelial tumours, including breast cancer.
Bergum, Christopher, Boerner, Julie, Colombo, Éloïc, Lang, Julie E, Leduc, Richard, List, Karin, Marsault, Eric, Molinolo, Alfredo A, Murray, Andrew S, Tanabe, Lauren M, Varela, Fausto A, Zoratti, Gina L   +11 more
core   +1 more source

Turing Instability and Pattern Formation in an Activator-Inhibitor System with Nonlinear Diffusion

, 2014
In this work we study the effect of density dependent nonlinear diffusion on pattern formation in the Lengyel--Epstein system. Via the linear stability analysis we determine both the Turing and the Hopf instability boundaries and we show how nonlinear ...
Gambino, G., Lombardo, M. C., Sammartino, M.   +2 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source