Results 121 to 130 of about 234,823 (303)

Pulse interactions and self-replication in activator-inhibitor type reaction-diffusion systems

, 2006
This phenomenon of self-replicating spots and pulses was discovered in the Gray-Scott model and in a series of gel reactor experiments. In this talk, I will present some analytical and numerical results for pulse dynamics and self-replication in one and ...
Kaper, Tasso
core  

Global feedback control of Turing patterns in network-organized activator-inhibitor systems

, 2012
Results of the first systematic study on feedback control of nonequilibrium pattern formation in networks are reported. Effects of global feedback control on Turing patterns in network-organized activator-inhibitor system have been investigated.
S. Hata, Mikhailov, A., Hata, S., H. Nakao, A. S. Mikhailov, Nakao, H.   +5 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Analyzing the dynamic behavior of the Gierer–Meinhardt model using finite difference method

AIP Advances
In this paper, a numerical computation method for the Gierer–Meinhardt model in two-dimensional space diffusion with homogeneous Neumann boundary conditions, considering the interaction between activator and inhibitor substances, is proposed.
Jianping Lv, Hefang Jing
doaj   +1 more source

Stationary Multiple Spots for Reaction-Diffusion Systems

, 2007
In this paper, we review analytical methods for a rigorous study of the existence and stability of stationary, multiple spots for reaction-diffusion systems.
Winter, M, Juncheng Wei, Matthias Winter, Wei, J   +3 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Tentacle morphogenesis in hydra [PDF]

, 1990
Differentiation of sensory nerve cells in tentacles of Hydra magnipapillata was investigated using the monoclonal antibody NV1. NV1+ sensory nerve cells form specific complexes with battery cells in tentacles.
Hobmayer, Engelbert, Holstein, Thomas W., David, Charles N.   +2 more
core  

Synchronization in coupled cells with activator-inhibitor pathways

, 2007
The functional dynamics exhibited by cell collectives are fascinating examples of robust, synchronized, collective behavior in spatially extended biological systems.
Sinha, Somdata, Sinha, Sudeshna, Rajesh, S.   +2 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Expression of type 1 plasminogen activator inhibitor in renal tissue in murine lupus nephritis

, 1995
Expression of type 1 plasminogen activator inhibitor in renal tissue in murine lupus nephritis. Many renal diseases are associated with fibrin deposition in the glomeruli, a situation that reflects an abnormality in the balance between the coagulation ...
Burlingame, Rufus, Keeton, Mark, Ahn, Curie, Loskutoff, David J., Eguchi, Yutaka   +4 more
core   +1 more source