Results 51 to 60 of about 1,301,037 (308)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

Ephalometrıc Evaluatıon Of The Immedıate Changes In Cervıcal Structures After The Applıcatıon Of The Actıvator

open access: yesTurkish Journal of Orthodontics, 1990
This study was accomplished to determine the 'postural adaptations of the structures related to cervical vertebrae, after changing the functional conditions with the activator.
Rüştiye Sürücü   +2 more
doaj   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel   +3 more
wiley   +1 more source

Effects of the Activator and Twin Block on Facial Soft Tissue Thickness in Class II Division 1 Patients

open access: yesTurkish Journal of Orthodontics, 2014
Objective:The purpose of this study was to evaluate and compare the effects of the activator and Twin Block appliances on soft tissue thickness in Class II division 1 patients.Materials and Methods:Soft tissue thickness measurements were obtained from ...
Mehmet Akın   +3 more
doaj   +1 more source

Reduced Order Optimal Control of the Convective FitzHugh-Nagumo Equation

open access: yes, 2019
In this paper, we compare three model order reduction methods: the proper orthogonal decomposition (POD), discrete empirical interpolation method (DEIM) and dynamic mode decomposition (DMD) for the optimal control of the convective FitzHugh-Nagumo (FHN ...
Karasözen, Bülent   +2 more
core   +1 more source

PAI1 blocks NMDA receptor-mediated effects of tissue-type plasminogen activator on cell signaling and physiology [PDF]

open access: yes, 2018
The fibrinolysis proteinase tissue-type plasminogen activator (tPA, also known as PLAT) triggers cell signaling and regulates cell physiology. In PC12 cells, Schwann cells and macrophages, the N-methyl-D-aspartate receptor (NMDA-R) mediates tPA signaling.
Azmoon, Pardis   +5 more
core   +2 more sources

The Treatment Effects Of Open-Bıte Cases Wıth Combınatıon Of Actıvator, Occıpıtal Headgear, And Vertıcal Chın-Cap On Soft Tıssue Profıle

open access: yesTurkish Journal of Orthodontics, 1997
This study was held on totally 68 lateral cephalograins and hand-wrist radiograms of 34 individuals. The materials of this study were obtained from the individuals at the beginning and at the end of treatment and controls.
Zahir Altuğ, Meliha Rübendüz
doaj   +1 more source

Regulation of MYB Transcription Factors of Anthocyanin Synthesis in Lily Flowers

open access: yesFrontiers in Plant Science, 2021
Flower color is the decisive factor that affects the commercial value of ornamental flowers. Therefore, it is important to study the regulation of flower color formation in lily to discover the positive and negative factors that regulate this important ...
Xiaojuan Yin   +10 more
doaj   +1 more source

A multiscale hybrid mathematical model of epidermal-dermal interactions during skin wound healing. [PDF]

open access: yes, 2019
Following injury, skin activates a complex wound healing programme. While cellular and signalling mechanisms of wound repair have been extensively studied, the principles of epidermal-dermal interactions and their effects on wound healing outcomes are ...
Chen, Weitao   +7 more
core   +1 more source

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