Results 71 to 80 of about 1,063,100 (311)
Targeted deficiency of the transcriptional activator Hnf1 alpha alters subnuclear positioning of its genomic targets [PDF]
, 2008 DNA binding transcriptional activators play a central role in gene-selective regulation. In part, this is mediated by targeting local covalent modifications of histone tails.
Luco, Reini F. +14 more
core +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Activation studies of the β-carbonic anhydrases from Escherichia coli with amino acids and amines
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 A β-carbonic anhydrase (CA, EC 4.2.1.1) from the widespread bacterium Escherichia coli (EcoCAβ), encoded by the CynT2 gene, has been investigated for its catalytic properties and enzymatic activation by a panel of amino acids and amines.
Alessio Nocentini +5 more
doaj +1 more source
Jurnal Rekayasa Proses, 2020 Oil palm shell is one of biomass-wastes which is abundantly found in palm oil industries. Its economical value can be enhanced by converting it into hydrochar using a hydrothermal carbonization process (HTC).
Aziz Askaputra +1 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Urokinase Plasminogen Activator
, 2016 The urokinase plasminogen activator system (uPAS) is an essential mechanism in a wide variety of biological processes such as fibrinoloysis, inflammation, atherosclerotic plaque formation, matrix remodeling during wound healing, tumor invasion ...
Ali Salajegheh, Salajegheh, Ali
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Time of admission to PICU in relation to plasminogen-activator-inhibitor-1 levels and outcome.
, 2016 (A) Patients admitted between 6:00 am and 12:00 am had higher plasminogen-activator-inhibitor-1 levels than patients admitted at night (P = 0.019) or in the afternoon (P = 0.007). (PAI-1 level on y-axis in logarithmic scale.
Marjon H. Cnossen (3366872) +4 more
core +1 more source
Turkish Journal of Orthodontics, 1997 This study was held on totally 68 lateral cephalograms and hand-wrist radiograms of 34 individuals. Nineteen of individuals were treatment group with skeletal and dental open-bite characteristics (13 girls, 6 boys).
Meliha Rübendüz, Zahir Altuğ
doaj +1 more source
Jurnal Riset Industri Hasil Hutan, 2018 An added value of bamboo charcoal that is commonly used as an energy source could be increased by the addition of activator and metal doping. The objective of this research was to analyze the effect of the addition of activator and doping to the ...
Rizka Karima, Nurmilatina Nurmilatina
doaj +1 more source