Results 91 to 100 of about 1,063,100 (311)
Turkish Journal of Orthodontics, 1996 The disadvantages of fixed Herbst appliance, such as hgiene problems, limitations of mandibular functional movements, etc., leads certain authors to design a new removable appliance having same mechanic principals.
Eray Erdoğan
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Human NCU-G1 can function as a transcription factor and as a nuclear receptor co-activator-0
, 2011 Copyright information:Taken from "Human NCU-G1 can function as a transcription factor and as a nuclear receptor co-activator"http://www.biomedcentral.com/1471-2199/8/106BMC Molecular Biology 2007;8():106-106.Published online 16 Nov 2007PMCID:PMC2233640 ...
Winnie Eskild (68339) +8 more
core +1 more source
2-[2-(4-(trifluoromethyl)phenylamino)thiazol-4-yl]acetic acid (Activator-3) is a potent activator of AMPK [PDF]
, 2018 AMPK is considered as a potential high value target for metabolic disorders. Here, we present the molecular modeling, in vitro and in vivo characterization of Activator-3, 2-[2-(4-(trifluoromethyl)phenylamino)thiazol-4-yl]acetic acid, an AMP mimetic and ...
Bulusu, Gopalakrishnan +11 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Human NCU-G1 can function as a transcription factor and as a nuclear receptor co-activator-6
, 2011 Copyright information:Taken from "Human NCU-G1 can function as a transcription factor and as a nuclear receptor co-activator"http://www.biomedcentral.com/1471-2199/8/106BMC Molecular Biology 2007;8():106-106.Published online 16 Nov 2007PMCID:PMC2233640 ...
Winnie Eskild (68339) +8 more
core +1 more source
The study of molecular markers for the progression of Barrett's Oesophagus to adenocarcinoma to identify markers that can be used as diagnostic tools. [PDF]
, 2002 Barrett's oesophagus is a complication of gastro-oesophageal reflux disease and is the single most important predisposing factor for the development of adenocarcinoma of the oesophagus.
Cadd, Verity Anne
core +3 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Tentacle morphogenesis in hydra [PDF]
, 1990 Stimulation of tentacle-specific cell differentiation by the neuropeptide head activator was investigated in Hydra magnipapillata. Tentacle-specific sensory nerve cells were identified by a monoclonal antibody, NV1.
Hobmayer, Engelbert +2 more
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