Results 81 to 90 of about 1,063,100 (311)

Active Matter [PDF]

open access: yesThe European Physical Journal E, 2013
The study of systems with sustained energy uptake and dissipation at the scale of the constituent particles is an area of central interest in nonequilibrium statistical physics. Identifying such systems as a distinct category -- Active Matter -- unifies our understanding of autonomous collective move- ment in the living world and in some surprising ...
Golestanian, R. ; https://orcid.org/0000-0002-3149-4002   +1 more
openaire   +5 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Discovering anti-platelet drug combinations with an integrated model of activator-inhibitor relationships, activator-activator synergies and inhibitor-inhibitor synergies. [PDF]

open access: yes, 2015
Identifying effective therapeutic drug combinations that modulate complex signaling pathways in platelets is central to the advancement of effective anti-thrombotic therapies.
Denis C. Shields (18564)   +17 more
core   +1 more source

AN INFLUENCE OF THE d311 EFFECT ON THE BEHAVIOR OF THE CANTILEVER BEAM-SHAPED PIEZOELECTRIC ACTIVATOR MADE OF TWO LAYERS OF PVDF WITH INVERSE POLARITY [PDF]

open access: yesApplied Computer Science, 2014
In the present work an example of the numerical modeling of electro-mechanical coupling of the activator in the form of cantilever beam made of two layers PVDF subjected to an inverse polarity is described.
Andrzej TETER   +2 more
doaj  

Structures, substrates, and regulators of mammalian Sirtuins – opportunities and challenges for drug development

open access: yesFrontiers in Pharmacology, 2012
Sirtuins are NAD+-dependent protein deacetylases regulating metabolism, stress responses, and aging processes. Mammalia have seven Sirtuin isoforms, Sirt1-7, which differ in their substrate specificities and subcellular localizations.
Sebastien eMoniot   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Cyclo19,31[D-Cys19]-uPA19-31 is a potent competitive antagonist of the interaction of urokinase-type plasminogen activator with its receptor (CD87) [PDF]

open access: yes, 2001
Urokinase-type plasminogen activator (uPA) represents a central molecule in pericellular proteolysis and is implicated in a variety of physiological and pathophysiological processes such as tissue remodelling, wound healing, tumor invasion, and ...
Kellermann, Josef   +10 more
core   +1 more source

The Evaluatıon Of The Changes Occurıng In The Vertıcal Dırectıon Of The Face In Cases Treated Wıth Actıvator + Occıpıtal Headgear Combınatıon

open access: yesTurkish Journal of Orthodontics, 1989
The aim of this study was to evaluate the vertical skeletal and dentoalveolar changes in the Class II Division 1 cases treated with the activator + occipital headgear combination.
Zahir Altuğ   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The Effects of Activator Treatment on the Lip Profile

open access: yes, 2005
The aim of this study was to investigate the changes of soft tissue profile in Class II division 1 cases, treated with activator and to compare the results with those of a control group.
Selim Arıcı, Mete Özer
core   +1 more source

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