Results 251 to 260 of about 3,963,692 (395)

Genetics of common variable immunodeficiency: role of transmembrane activator and calcium modulator and cyclophilin ligand interactor [PDF]

, 2015
Harindra D. Sathkumara, N. R. De Silva, Shiroma M. Handunnetti, Aruna Dharshan De Silva   +3 more
openalex   +1 more source

Epileptic and developmental disorders of the speech cortex: ligand/receptor interaction of wild-type and mutant SRPX2 with the plasminogen activator receptor uPAR.

Human Molecular Genetics, 2008
Barbara Royer-Zemmour, Magali Ponsole-Lenfant, Hyam Gara, P. Roll, C. Lévêque, A. Massacrier, G. Ferracci, J. Cillario, A. Robaglia-Schlupp, R. Vincentelli, P. Cau, P. Szepetowski   +11 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Exploring the genetic frontier: Unraveling ANRIL, PAI-1, and HNF1α in stroke progression. [PDF]

PLoS One
Hamadi A, Mir R, Al-Amer OM, Alasseiri M, Dobie G, Elfaki I, AlZamzami W, Alatawi S, Oyouni AAA, Alanazi MA, Muthupandian S.   +10 more
europepmc   +1 more source

Targeted disruption of the mouse sphingolipid activator protein gene: a complex phenotype, including severe leukodystrophy and wide-spread storage of multiple sphingolipids.

Human Molecular Genetics, 1996
N. Fujita, K. Suzuki, M. Vanier, B. Popko, N. Maeda, A. Klein, M. Henseler, K. Sandhoff, H. Nakayasu   +8 more
semanticscholar   +1 more source

Control of Genetic Activity

The American Biology Teacher, 1969
openaire   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

CrebA regulation of secretory capacity: genome-wide transcription profiling coupled with in vivo DNA binding studies. [PDF]

Genetics
Jackson DJ, Peng D, Shinde SA, Holenarasipura A, Ajay V, Cahan P, Andrew DJ.   +6 more
europepmc   +1 more source