Results 351 to 360 of about 3,917,874 (426)

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

RcsF-independent mechanisms of signaling within the Rcs phosphorelay. [PDF]

PLoS Genet
Petchiappan A, Majdalani N, Wall E, Gottesman S.   +3 more
europepmc   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

Prioritizing Parkinson's disease risk genes in genome-wide association loci. [PDF]

NPJ Parkinsons Dis
Lange LM, Cerquera-Cleves C, Schipper M, Panagiotaropoulou G, Braun A, Kraft J, Awasthi S, Bell N, Posthuma D, Ripke S, Blauwendraat C, Heilbron K.   +11 more
europepmc   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Cohort profile: the Genetics of Glucose regulation in Gestation and Growth (Gen3G) - a prospective prebirth cohort of mother-child pairs in Sherbrooke, Canada, 3-year and 5-year follow-up visits. [PDF]

BMJ Open
Taschereau A, Doyon M, Arguin M, Allard C, Desgagné V, Cote AM, Massé É, Jacques PÉ, Perron P, Hivert MF, Bouchard L.   +10 more
europepmc   +1 more source

Indications of the SERPINE 1 variant rs1799768's role in anti-VEGF therapy resistance in neovascular age-related macular degeneration. [PDF]

PLoS One
Çevik MÖ, Mert Altuntaş Z, Çevik SG.
europepmc   +1 more source

Genetics, sex and the use of platelet-rich plasma influence the development of arthrofibrosis after anterior cruciate ligament reconstruction. [PDF]

J Exp Orthop
Sánchez M, Yarza I, Jorquera C, Aznar JM, de Dicastillo LL, Valente C, Andrade R, Espregueira-Mendes J, Celorrio D, Aizpurua B, Azofra J, Delgado D.   +11 more
europepmc   +1 more source

Small interfering RNAs generated from the terminal panhandle structure of negative-strand RNA virus promote viral infection. [PDF]

PLoS Pathog
Zhao W, Li Q, Sun M, Luo L, Zhang X, Cui F.   +5 more
europepmc   +1 more source

Mitochondria and NLRP3: To die or inflame. [PDF]

Immunity
Yang S, Huang G, Ting JP.
europepmc   +1 more source