Results 141 to 150 of about 14,005,924 (265)

The Association of Individual Characteristics with Success and Failure of U. S. Army Recruiters

Operations Research ...
Coleman, F. David (Creatorcre)
core  

An economic evaluation of universal and targeted case-finding strategies for identifying antenatal depression: a model-based analysis comparing common case-finding instruments.

Half of women with depression in the perinatal period are not identified in routine care, and missed cases reflect inequalities in other areas of maternity care.
Chew-Graham, Carolyn A, Camacho, Elizabeth M, Eisner, Emily, Littlewood, Elizabeth, Shields, Gemma E, Gilbody, Simon, Watson, Kylie, McMillan, Dean, Ali, Shehzad   +8 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Treatment outcomes of individuals with tuberculosis identified from mobile chest X-ray-based active case finding in Pakistan. [PDF]

Public Health Action
Zaidi SMA, Horton KC, Esmail H.
europepmc   +1 more source

An Annotated Bibliography: Applications of Operations research to Educational Systems

Operations Research ...
Balinsky, Warren (Creatorcre)
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Computer-aided detection pragmatic threshold calibration in TB active case finding: A mixed-methods study in Tondo, Manila. [PDF]

PLOS Glob Public Health
Carnimeo V, Phillips EY, Galvan DK, Camelique O, Roxas MR, Duka M, Pardilla GF, Recidoro MJC, Castro RH, Hossain F, Huerga H, Hewison C, Min J.   +12 more
europepmc   +1 more source

The Accuracy in Estimating Truck Class Rates for Logistical Planning

Operations Research ...
Ballou, Ronald (Creatorcre)
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Diagnostic accuracy of TB-LAMP and smear microscopy for pulmonary TB in active case finding. [PDF]

IJTLD Open
Shimouchi A, Gopali RS, Maharjan B, Shrestha Y, Hirano Y, Shah NP, Ghimire P, Shrestha P, Okada K.   +8 more
europepmc   +1 more source