Results 151 to 160 of about 14,005,924 (265)

Applications of Multi-Attribute Utility Theory in the Health Care Delivery System Since 1970

Operations Research ...
Reisman, Arnold (Creatorcre), Chaudhuri, Durjoy K. (Creatorcre)   +1 more
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Active case finding for tuberculosis among Ukrainian soldiers by German armed forces. [PDF]

Eur Respir J
Pohl J, Gröschel MI, Neumann N, Tillmann A, Waldeck S, Schneider T, Overhoff D, Lange SG, Bucksch T, Peuker R, Rauschning D, Scheumann G, Scheit L, Schreiner M, Retro-TB-Bw-Study Group, Wenzel W, Kehe K, Friesen I, Dreyer V, Niemann S, Sander LE, Witzenrath M, Nouailles G, Zobel CM.   +23 more
europepmc   +1 more source

Analysis of Feedback Models of Higher Education Degree Production

Operations Research ...
Michenzi, Alfred R. (Creatorcre)
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Does active case finding detect TB early in programme settings? A national-level study in India. [PDF]

Public Health Action
Shewade HD, Kiran Pradeep S, Ravichandran P, Kiruthika G, Shah AN, Vadera B, Roddawar V, Mattoo SK, Iyer S, Tumu D, Chowdhury A, Devika S, Chadwick J, Vaidya RR, Singh P, Panda SK, Baig MA, Suma KV, Suleka M, Digal AK, Banerjee D, Prasanna ML, Waghela DY, Krishnaraj A, Kashyap P, Parmar JS, Mishra CK, Das S, Kumar A, Kumar A, Yadav S, Chetry S, Kumar A, Pathak M, Singh S, Tabrez S, Mehra P, Ramesh S, Bishnu B, Mahesh G, Rajesham A, Mishra BK, Chandra Tripathi U, Khayyam KU, Rade K, Rao R, Murhekar MV.   +46 more
europepmc   +1 more source

Anesthesiology Manpower Planning Study Phase III - Final Report

Operations Research ...
Reisman, A. (Creatorcre), Emmons, H. (Creatorcre), Lin, M. (Creatorcre), George, T. (Creatorcre), Darakhanavala, P. (Creatorcre), Dean, B. V. (Creatorcre), deKluyver, C. A. (Creatorcre), Gravenstein, J. S. (Creatorcre), Staub, F. (Creatorcre), Rasmussen, J. (Creatorcre)   +9 more
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Factors associated with tuberculosis symptom reporting among persons deprived of liberty in Brazil during active case finding: a cross-sectional study. [PDF]

BMJ Public Health
Bampi JVB, Salindri AD, Gonçalves IB, Coene JS, Croda MG, da Silva AM, Jung E, Busatto C, de Oliveira RD, Cunha EAT, Andrews JR, Croda J.   +11 more
europepmc   +1 more source

Annotated Bibliography on Methods for Evaluating Basic Research Projects

Operations Research ...
Davis, J. Bruce (Creatorcre)
core