Results 81 to 90 of about 82,330 (304)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

A comprehensive review of fault diagnosis and fault-tolerant control techniques for modular multi-level converters

Science Progress, 2022
Background Many faults occur in the modular multi-level converters (MMCs), including unbalancing capacitor voltage, lower and upper arm unbalancing, the line to line voltage unbalancing, sensors and actuators fault, system fault, and sub-modules fault in
Faizan Ahmad, Muhammad Adnan, Arslan Ahmed Amin, Muhammad Gufran Khan   +3 more
doaj   +1 more source

Robust Gain-Scheduled Fault Tolerant Control for a Transport Aircraft [PDF]

This paper presents an application of robust gain-scheduled control concepts using a linear parameter-varying (LPV) control synthesis method to design fault tolerant controllers for a civil transport aircraft.
Gregory, Irene, Shin, Jong-Yeob
core   +2 more sources

Observer-based fault-tolerant control for a class of networked control systems with transfer delays [PDF]

, 2011
not availableZehui Mao, Bin Jiang, Peng ...
Bin Jiang, Chen, Gu, He, He, Jiang, Jiang, Mahmoud, Mahmoud, Mahmoud, Mahmoud, Mao, Mao, Nešić, Peng Shi, Sheng, Shi, Vesely, Xia, Yang, Yang, Yang, Zehui Mao, Zhang, Zheng, Zhou   +25 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

A Fault-Tolerant Emergency-Aware Access Control Scheme for Cyber-Physical Systems [PDF]

, 2011
Access control is an issue of paramount importance in cyber-physical systems (CPS). In this paper, an access control scheme, namely FEAC, is presented for CPS. FEAC can not only provide the ability to control access to data in normal situations, but also
Lu, Dongze, Wu, Guowei, Xia, Feng, Yao, Lin   +3 more
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

A dynamic prognosis algorithm in distributed fault tolerant model predictive control [PDF]

, 2014
This paper presents a dynamic prognosis algorithm in distributed fault tolerant model predictive control (DFTMPC). The dynamic prognosis, which means predicting the trajectories of process variables under distributed model predictive control, is ...
Jamsa-Jounela, Sirkka-Liisa, Yu, Miao, Zakharov, Alexey   +2 more
core   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Active Fault-Tolerant Control Based on Multiple Input Multiple Output-Model Free Adaptive Control for Four Wheel Independently Driven Electric Vehicle Drive System

Applied Sciences, 2019
To solve the problems with the existing active fault-tolerant control system, which does not consider the cooperative control of the drive system and steering system or accurately relies on the vehicle model when one or more motors fail, a multi-input ...
Yugong Luo, Yun Hu, Fachao Jiang, Rui Chen, Yongsheng Wang   +4 more
doaj   +1 more source