Results 101 to 110 of about 603,998 (309)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Geospatial technology applications in Quaternary Science

Quaternary Science Advances, 2022
Ajay Kumar Taloor, Girish Ch Kothyari, Ajanta Goswami, Akhilesh Mishra   +3 more
doaj   +1 more source

Hazard analysis of future surface displacements on active faults based on the recurrence interval of strong earthquakes

Open Geosciences
Coseismic surface displacements pose a serious threat to the safety of linear infrastructures on active faults. A reasonable evaluation of surface displacements on active faults is important.
Zhou Qingyun, Liu Jingnan, Tian Peng, Luo Weidong, Bai Xianfu, Yang Yue, Zou Zhenyu   +6 more
doaj   +1 more source

Active Fault Isolation for Multimode Fault Systems Based on a Set Separation Indicator. [PDF]

Entropy (Basel), 2023
Han K, Lu S, Liu Z, Wang Z.
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Editorial: Understanding the marginal seas of northeast asia for tectonics and submarine geohazards

Frontiers in Earth Science, 2022
Kwang-Hee Kim, Han-Joon Kim, Tianyao Hao, Tianyao Hao, Tianyao Hao, Xunhua Zhang   +5 more
doaj   +1 more source

Late quaternary slip rate and paleoseismic sequence of the Cuopuhu section of the Litang-Yidun fault, western Sichuan, China

Dizhi lixue xuebao
Objective  The Litang-Yidun fault is a left-lateral strike-slip active fault zone extending approximately 130 km in the Sichuan-Yunnan rhombic block in the Holocene.
WANG Shiyuan, WANG Jing, LI Fupeng, TAO Zhigang, LIANG Mingjian, LIU Shao, QU Miao, ZHANG Liwen, ZENG Weizu, JIN Yunxia   +9 more
doaj   +1 more source

Active sensor fault tolerant output feedback tracking control for wind turbine systems via T-S model [PDF]

, 2014
This paper presents a new approach to active sensor fault tolerant tracking control (FTTC) for offshore wind turbine (OWT) described via Takagi–Sugeno (T–S) multiple models.
Patton, Ron J., Shaker, Montadher Sami
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Editorial note for the Geodesy and Geodynamics journal special issue: Remote Sensing and GIS applications in crustal deformation and neotectonics

Geodesy and Geodynamics, 2022
Ajay Kumar Taloor, Girish Chandra Kothyari, Shangmin Zhao, Rajwant, Mayank Joshi   +4 more
doaj   +1 more source