Results 101 to 110 of about 3,561,124 (293)

Adaptive and Robust Fault-Tolerant Tracking Control of Contact force of Pantograph-Catenary for High-Speed Trains [PDF]

, 2015
This paper presents a modified multi-body dynamic model and a linear time-invariant model with actuator faults (loss of effectiveness faults, bias faults) and matched and unmatched uncertainties.
Yan, Xinggang, Zhang, Kang-K, Mao, Zehui, Jiang, Bing   +3 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Hazard analysis of future surface displacements on active faults based on the recurrence interval of strong earthquakes

Open Geosciences
Coseismic surface displacements pose a serious threat to the safety of linear infrastructures on active faults. A reasonable evaluation of surface displacements on active faults is important.
Zhou Qingyun, Liu Jingnan, Tian Peng, Luo Weidong, Bai Xianfu, Yang Yue, Zou Zhenyu   +6 more
doaj   +1 more source

Reinforcement learned adversarial agent (ReLAA) for active fault detection and prediction in space habitats. [PDF]

NPJ Microgravity, 2023
Overlin M, Iannucci S, Wilkins B, McBain A, Provancher J.   +4 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Geospatial technology applications in Quaternary Science

Quaternary Science Advances, 2022
Ajay Kumar Taloor, Girish Ch Kothyari, Ajanta Goswami, Akhilesh Mishra   +3 more
doaj   +1 more source

Late quaternary slip rate and paleoseismic sequence of the Cuopuhu section of the Litang-Yidun fault, western Sichuan, China

Dizhi lixue xuebao
Objective  The Litang-Yidun fault is a left-lateral strike-slip active fault zone extending approximately 130 km in the Sichuan-Yunnan rhombic block in the Holocene.
WANG Shiyuan, WANG Jing, LI Fupeng, TAO Zhigang, LIANG Mingjian, LIU Shao, QU Miao, ZHANG Liwen, ZENG Weizu, JIN Yunxia   +9 more
doaj   +1 more source

Reaktivitas Sesar Kaligarang, Semarang

Indonesian Journal on Geoscience, 2014
http://dx.doi.org/10.17014/ijog.vol3no3.20082Kaligarang Fault which cuts across Semarang City in a north-south direction has been activated for long periods.
S. Poedjoprajitno, J. Wahyudiono, A. Cita   +2 more
doaj   +1 more source

Active fault-tolerant anti-input saturation control of a cross-domain robot based on a human decision search algorithm and RBFNN. [PDF]

Front Neurorobot, 2023
Wang K, Liu Y, Huang C.
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source