Results 141 to 150 of about 676,585 (361)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Editorial: Understanding the marginal seas of northeast asia for tectonics and submarine geohazards

Frontiers in Earth Science, 2022
Kwang-Hee Kim, Han-Joon Kim, Tianyao Hao, Tianyao Hao, Tianyao Hao, Xunhua Zhang   +5 more
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Design of Active Fault-Tolerant Control System for Air-Fuel Ratio control of Internal Combustion engine using nonlinear regression-based observer model. [PDF]

PLoS One, 2022
Alsuwian T, Amin AA, Iqbal MS, Qadir MB, Almasabi S, Jalalah M.   +5 more
europepmc   +1 more source

Morphological analysis of volcanic cones and its implication to Quaternary tectonics of the Jeju Island (South Korea)

Quaternary Science Advances
The morphological characteristics and distribution of volcanic cones of Jeju Island in Korea could be controlled by several factors, including stress field in the substrate and subsurface fractures. Controlling fractures, however, might not be visible on
Francois Hategekimana, Sambit Prasanajit Naik, Young-Seog Kim   +2 more
doaj  

Definitions, Classification Schemes for Active Faults, and Their Application

Geosciences
Active faults are generally defined as faults that have moved in the past and will continue to be active in the future. They are expected to cause deformation and potential disasters if they are localized close to human activities.
Zhonghai Wu, Mengmeng Hu
doaj   +1 more source

Anticipating Degradation: A Predictive Approach to Fault Tolerance in Robot Swarms [PDF]

arXiv
An active approach to fault tolerance is essential for robot swarms to achieve long-term autonomy. Previous efforts have focused on responding to spontaneous electro-mechanical faults and failures. However, many faults occur gradually over time. Waiting until such faults have manifested as failures before addressing them is both inefficient and ...
arxiv  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Nonlinear Predictive Motion Control for Autonomous Mobile Robots Considering Active Fault-Tolerant Control and Regenerative Braking. [PDF]

Sensors (Basel), 2022
Hang P, Lou B, Lv C.
europepmc   +1 more source

Chronological evidence and significance of Late Pleistocene activity in the Dongshan segment of the eastern branch of the Changle-Zhao'an fault belt

地质科技通报
Objective The Changle-Zhao'an fault zone is one of the primary active faults running along the coast of the Fujian Province. This fault zone has induced several destructive earthquakes and is thus a principal seismogenic structure in the Fujian Province.
Jisheng GUO, Yueqiang QIAO, Yong TANG, Song YU, Yanhong ZHA, Qing HU, Dongning LEI, Yongjian CAI   +7 more
doaj   +1 more source