Results 131 to 140 of about 3,561,124 (293)

Deformation under a Young Volcanic Covered Area in Southern Garut, Indonesia: Insight from 3D Gravity Modelling

Journal of Mathematical and Fundamental Sciences
Destructive earthquakes are frequently related to inland active faults. In recent years, a significant number of shallow earthquakes with low magnitude have occurred in southern Garut, West Java, Indonesia.
Ilham Arisbaya, Edy Wijanarko, Prihadi Sumintadireja, Warsa Warsa, Hendra Grandis   +4 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Breaking up the hanging wall of a rift-border fault: The 2009 Karonga earthquakes, Malawi [PDF]

The southern East African Rift has an unusually large seismogenic thickness (35–40 km), which is responsible for wide tilted basins and extremely long faults with the potential for M7-8 normal-faulting earthquakes.
Nissen, E., Craig, T. J., Robinson, D. P., Jackson, J., Biggs, J.   +4 more
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Geometry, evolution and scaling of fault relay zones in 3D using detailed observations from outcrops and 3D seismic data [PDF]

, 2011
A new surface attribute was developed during the course of the thesis, which enables fault-related deformation – specifically, the apparent dip of mapped horizons measured in a direction perpendicular to the average strike of a fault array (here termed ...
Long, Jonathan James, LONG, JONATHAN,JAMES   +1 more
core  

An analytical method for strength verification of buried steel pipelines at normal fault crossings

, 2011
The complex problem of strength verification of a buried steel pipeline crossing the trace of a normal active fault is treated analytically, and a refined methodology for the calculation of the axial and bending pipeline strains is presented. In essence,
G.D. Bouckovalas, Gkesouli, Vasiliki, Kouretzis, George P., Karamitros, DK, Karamitros, Dimitris K., G.P. Kouretzis, Kouretzis, GP, Bouckovalas, GD, V. Gkesouli, Bouckovalas, George D., D.K. Karamitros, Gkesouli, V   +11 more
core   +1 more source

Using reflection seismic technology to detect urban active faults in Guanzhong area

地球与行星物理论评
The neotectonic movement is active in Guanzhong Basin, with extensive development of ground fissures and active faults. To solve the problem of uncertain distribution of concealed active faults in urban areas, in this study, active fault detection was ...
Guangcai Li, Lixin Rong, Pei Li, Xiaojiang Wang, Chunxiang Jiang, Kai Wang   +5 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Characteristics of surface ruptures produced by recent major earthquakes on the Tibetan Plateau and its surrounding areas, and their tectonic implications

Dizhi lixue xuebao
Objective  Coseismic surface ruptures provide key evidence for identifying the seismogenic structures of earthquakes, elucidating crustal deformation mechanisms, and assessing seismic hazards.
PAN Jiawei, LI Haibing, LIU Fucai, CHEVALIER Marie-Luce, LIU Dongliang, LU Haijian, CHEN Peng, YANG Shaohua   +7 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source