Results 91 to 100 of about 118,708 (290)

Thinking beyond Vaccination: Promising Add-On Strategies to Active Immunization and Vaccination in Pandemics-A Mini-Review. [PDF]

Viruses, 2023
Tatzber F, Wonisch W, Resch U, Strohmaier W, Lindschinger M, Mörkl S, Cvirn G.   +6 more
europepmc   +2 more sources

TDP‐43 Aggregation: The Healthy‐Toxic Balance of the Prion‐Like Domain

Advanced Science, EarlyView.
TDP‐43 function relies on a delicate balance between reversible phase‐separated states and irreversible aggregation. Under physiological conditions, TDP‐43 forms dynamic droplets and oligomers that support normal cellular functions. In pathological contexts, this balance shifts toward aberrant aggregation, leading to toxic species.
Luca Zangrando, Emanuele Buratti, Francesca Paron   +2 more
wiley   +1 more source

Expanded Programme on Immunization in Iran: Last 3 Decades Achievements from 1979 to 2008 [PDF]

Iranian Journal of Public Health, 2009
Expanded Programme on Immunization (EPI) in I.R.Iran began in 1984 after establishing of health network for PHC all over the country and reached to high & accepted coverage rates for active immunization of infants against vaccine prevent­able diseases ...
MM Gouya
doaj   +1 more source

Structural asymmetry in knowledge of active and passive tetanus immunization among frontline healthcare workers: Implications for adult booster policy in China

Human Vaccines & Immunotherapeutics
Despite sustained high childhood tetanus vaccination coverage in China, adult booster immunization has not been institutionalized, leaving a substantial immunity gap.
Quanjun Fang, Jilai Mao, Longcai Yu, Xiaoying Gong, Canjie Zheng, Guoping Cao, Zhiying Yin   +6 more
doaj   +1 more source

A Chemically Defined Four‐Component Self‐Adjuvanting Tn Vaccine Activating Mincle, FcγR, and CD206 for Enhanced Antitumor Immunity

Advanced Science, EarlyView.
A fully synthetic four‐component vaccine has been developed combining Tn antigen, vizantin (Mincle agonist), rhamnose (antibody recruitment), and mannose (CD206 targeting). By synergistically activating Mincle, FcγR, and CD206 pathways, it elicits strong IgG switching and cytotoxic T‐cells, significantly inhibiting tumors in mice.
Wenbo Ming, Renyu Zhang, Xiaohui Li, Guiqi Li, Yu Niu, Deying Yang, Xiang Luo, Jun Liao, Zhongqiu Liu, Guochao Liao   +9 more
wiley   +1 more source

Active immunization against nicotine dependence

, 2010
Tobacco smoking is the largest preventable cause of morbidity and premature mortality in the world. Although its medical consequences are well documented, 20-45% of the adult population in the European countries remains tobacco smokers.
Sabina De Villiers (19525150)
core  

Nonamyloid-beta active immunization for the treatment of Alzheimer\u27s disease

INTRODUCTION: Alzheimer\u27s disease (AD) is characterized by the formation of senile plaques composed of amyloid-beta (Aβ) peptides and the intraneuronal accumulation of neurofibrillary tangles composed of abnormal, hyperphosphorylated tau proteins ...
Sabbagh, Marwan N, Triplett, Olivia, Decourt, Boris, Varda, Nicole   +3 more
core   +1 more source

Eye‐Brain Neuroimmune Axis Enables Long‐Term Survival in Glioblastoma by Modulating Brain Immune Surveillance and Neuronal Excitability

Advanced Science, EarlyView.
The eye–brain neuroimmune axis triggers immune activation and disrupts pathological neuronal connectivity to extend glioblastoma survival. ABSTRACT As an anatomical extension of the central nervous system (CNS), the eye harbors rich neural and immune interfaces with the brain. However, the integrated immunological and neurological nexus between the eye
Mingyue Cui, Lulu Qian, Binbin Chu, Xuan Qin, Menglin Wu, Minke Wu, Tongyu He, Baochuan Zhang, Bin Song, Yao He   +9 more
wiley   +1 more source

Target Tissue Effects of Active Immunization of Heifers Against Steroids

, 1985
Gonadal steroids mediate many responses throughout the body, many of which may have economic considerations. Antibodies made against steroids by active immunization have provided unique tools to begin to identify steroid target tissues and understand ...
Ferrell, Calvin L., Schanbacher, Bruce D., Wise, Thomas H.   +2 more
core   +1 more source

Rinderpest Immunity in Calves: II. Active Immunization [PDF]

Epidemiology and Infection, 1958
Calves which were the progeny of rinderpest-susceptible dams were inoculated with lapinized rinderpest virus when 1 day to 2 months old. Their serological response, as measured by neutralizing antibody titre 21 days later, did not differ from that of adult susceptible cattle.In calves born of rinderpest-immune cows, the serological response to ...
openaire   +2 more sources