Results 151 to 160 of about 3,928,328 (244)

Economic evidence of alternative formulations and routes of administration for identical active pharmaceutical ingredient: a systematic review. [PDF]

Health Econ Rev
Shao H, Jiang Y, Zhao M, Tang W.
europepmc   +1 more source

AI‐enabled engineering of hesperidin/ursodeoxycholic acid nanomedicine for synergistic treatment of drug‐induced liver injury

Smart Molecules, EarlyView.
An AI‐driven framework integrating disease‐network analysis, direction‐aware molecular screening, and carrier‐free co‐assembly engineering enables nanomedicine design. The dual‐constraint deep learning model predicts API–target affinity and regulatory direction to prioritize complementary APIs.
Kai Xiao, Meng Fan, Haoyu Zheng, Boyuan Gu, Shaowen Wang, Ziping Wu, Shiming Zhang, Xin Zhao, Wensheng Zhang, Quanxin Ning, Sigen A, Chao Yang, Huayi Sun, Ren Mo, Dan Shao   +14 more
wiley   +1 more source

Prevalence of Unregistered, Substandard, and Falsified Veterinary Antimicrobials in Ethiopia: A National Postmarket Quality Surveillance Study. [PDF]

Vet Med Int
Tefera B, Bacha B, Tefera N, Uma G, Setegn T, Belete B, Daba D, Jemal D, Tefera Y, Bedu H, Tilki T, Hailemichael D, Kebede S, Jemal H, Marew T, Teshome D, Gedif T, Gelaye E, Andualem T, Ashenef A.   +19 more
europepmc   +1 more source

Proximity Proteomics Maps Candidate Cellular Uptake Pathways for Cell‐Derived Nanovesicles

Small Methods, EarlyView.
TurboID‐based dual‐sided proteomics compares mechanically generated cell‐derived nanovesicles with naturally secreted small extracellular vesicles. Vesicle proteomes define candidate interaction signatures, while recipient‐cell proximity labelling identifies exposure‐associated proteins.
Eisuke Kanao, Ryosuke Mizuta, Saki Tarao, Yukika Hara, Yuka Li, Kazunari Akiyoshi, Yasushi Ishihama, Koshi Imami, Yoshihiro Sasaki   +8 more
wiley   +1 more source

How Low Could Semaglutide Prices Fall? An Analysis of Production Cost and Implications for Global Access. [PDF]

Obesity (Silver Spring)
Levi J, Cross S, Ramesh N, Venter F, Hill A.   +4 more
europepmc   +1 more source

Synergistic and Antagonistic Effects of Chemical Pollutants and Parasitic Fungi on Cyanobacterial Metabolism

Environmental Toxicology, EarlyView.
ABSTRACT Freshwater ecosystems are increasingly impacted by anthropogenic pollutants, including the widely used herbicide metolachlor (MET) and cigarette butt (CB) litter. Parasites represent an additional biotic stressor that can modulate pollutant effects on their hosts.
Erika Berenice Martínez‐Ruiz, Jutta Fastner, Stephanie Spahr, Justyna Wolinska   +3 more
wiley   +1 more source

Quality by Design Approach to the Optimization of Cohesive Powder Blending in Direct Compression. [PDF]

Pharmaceutics
Przywara M, Leszczak P.
europepmc   +1 more source

Protective Effects of Bee Venom (Apis mellifera) Against Cadmium‐Induced Hepatorenal Toxicity, Oxidative Stress, and Anxiety‐Like Behavior in Rats

Environmental Toxicology, EarlyView.
ABSTRACT Cadmium (Cd) is a persistent environmental heavy metal and a major public health concern because it persists in the body for long periods and gradually accumulates in vital organs, particularly the liver, kidneys, and brain. Chronic Cd exposure promotes the excessive production of reactive oxygen species (ROS), which ultimately leads to ...
Soumaya Ghodbane, Chedli Ellijimi, Rym Elfessi, Ranya Hezzi, Khemaies Ben Rhouma, Hafedh Abdelmelek, Najet Srairi‐Abid, Mohsen Sakly, Riadh Marrouchi   +8 more
wiley   +1 more source

Development and Optimisation of a Stability-Indicating Analytical Method for Itraconazole in Drug Product by High-Performance Liquid Chromatography Using a QbD Approach. [PDF]

Pharmaceuticals (Basel)
Fraschi-Nieto A, Mula-Roldán X, Gavaldà-Cánovas L, Mercadé-Frutos D, García-Montoya E, Suñé-Pou M, Pérez-Lozano P.   +6 more
europepmc   +1 more source

Impact of Environmental Microparticles on Insect Olfaction

Environmental Toxicology, EarlyView.
ABSTRACT Terrestrial insects underpin key ecosystem services, including pollination, herbivory regulation, decomposition, nutrient cycling, and disease control. These functions depend on chemical communication that guides insects to food, mates, hosts, shelters, and oviposition sites while helping them avoid threats.
Steve B. S. Baleba, Danube K. N. Wandji, Yves H. Tchiechoua, Komi Mensah Agboka, Iman B. Hassaballa, Victor O. Omondi, Beatrice T. Nganso, Saliou Niassy, Souleymane Diallo, Merid N. Getahun   +9 more
wiley   +1 more source