Results 151 to 160 of about 4,119,069 (249)

Crystallization of active pharmaceutical ingredient on substrates

, 2014
Due to the demand of individualized pharmaceutical formulation, the application of drop printing (DP) technology on manufacturing of pharmaceutical devices has received extensive attention.
Hsu, Hsin-Yun
core  

Reactivity of Oxidized Porous Silicon with Calcium Ion in Aqueous Media: Stability, pH Behavior, and Host‐Guest Strategies

Small, EarlyView.
Oxidized porous silicon, composed of an elemental silicon porous skeleton coated with a silica shell, reacts with aqueous Ca2+ to generate a mixed silica–calcium silicate matrix that is remarkably efficient at trapping small molecules. With an emphasis on the engineering of controlled‐release drug delivery systems, this study identifies the factors ...
Ruhan Fan, Qinglin Yang, Michael J. Sailor   +2 more
wiley   +1 more source

When Does Magnesium Stearate Improve Carrier-Based Dry Powder Inhalers (DPI) Performance? A Critical Review of Material, Process, and Formulation Factors. [PDF]

Pharmaceuticals (Basel)
Rzewińska-Dąbrowska A, Wójcik K, Juszczyk E, Tratkiewicz E, Dorożyński P.   +4 more
europepmc   +1 more source

Reverse Micelles: The Gateway for Oral (Poly)Peptide Delivery

Small, EarlyView.
RM achieve superior oral peptide delivery through high loading capacity, strong lipophilicity, and a low‐hydration microenvironment that protects against enzymatic degradation. Meanwhile, dRM provides favorable permeation‐enhancing interactions and a consistent safety profile, collectively driving enhanced oral performance.
Marlene Ramona Schmidt, Melanie Lena Ebert, Andreas Bernkop‐Schnürch   +2 more
wiley   +1 more source

Toxicity of the Antiretrovirals Lamivudine, Dolutegravir, and Tenofovir on the Microalga <i>Chlorella vulgaris</i>. [PDF]

ACS Omega
Souza-Silva G, Alcantara M, Moreira C, Starling MC, Souza C, Nunes K, Pereira C, Mol M, Silveira M.   +8 more
europepmc   +1 more source

AI‐enabled engineering of hesperidin/ursodeoxycholic acid nanomedicine for synergistic treatment of drug‐induced liver injury

Smart Molecules, EarlyView.
An AI‐driven framework integrating disease‐network analysis, direction‐aware molecular screening, and carrier‐free co‐assembly engineering enables nanomedicine design. The dual‐constraint deep learning model predicts API–target affinity and regulatory direction to prioritize complementary APIs.
Kai Xiao, Meng Fan, Haoyu Zheng, Boyuan Gu, Shaowen Wang, Ziping Wu, Shiming Zhang, Xin Zhao, Wensheng Zhang, Quanxin Ning, Sigen A, Chao Yang, Huayi Sun, Ren Mo, Dan Shao   +14 more
wiley   +1 more source

Development and characterization of an Indacaterol/Tiotropium Bromide composite dry powder inhalation formulation for COPD. [PDF]

Pharm Sci Adv
Wang X, Xu X, Cheng C, Zheng J, Liu W, Xu Y, Xu J, Wu L, Sun X, Wang W, Fang H.   +10 more
europepmc   +1 more source

Protective Effects of Bee Venom (Apis mellifera) Against Cadmium‐Induced Hepatorenal Toxicity, Oxidative Stress, and Anxiety‐Like Behavior in Rats

Environmental Toxicology, EarlyView.
ABSTRACT Cadmium (Cd) is a persistent environmental heavy metal and a major public health concern because it persists in the body for long periods and gradually accumulates in vital organs, particularly the liver, kidneys, and brain. Chronic Cd exposure promotes the excessive production of reactive oxygen species (ROS), which ultimately leads to ...
Soumaya Ghodbane, Chedli Ellijimi, Rym Elfessi, Ranya Hezzi, Khemaies Ben Rhouma, Hafedh Abdelmelek, Najet Srairi‐Abid, Mohsen Sakly, Riadh Marrouchi   +8 more
wiley   +1 more source

Economic evidence of alternative formulations and routes of administration for identical active pharmaceutical ingredient: a systematic review. [PDF]

Health Econ Rev
Shao H, Jiang Y, Zhao M, Tang W.
europepmc   +1 more source

Impact of Environmental Microparticles on Insect Olfaction

Environmental Toxicology, EarlyView.
ABSTRACT Terrestrial insects underpin key ecosystem services, including pollination, herbivory regulation, decomposition, nutrient cycling, and disease control. These functions depend on chemical communication that guides insects to food, mates, hosts, shelters, and oviposition sites while helping them avoid threats.
Steve B. S. Baleba, Danube K. N. Wandji, Yves H. Tchiechoua, Komi Mensah Agboka, Iman B. Hassaballa, Victor O. Omondi, Beatrice T. Nganso, Saliou Niassy, Souleymane Diallo, Merid N. Getahun   +9 more
wiley   +1 more source