Results 191 to 200 of about 4,119,069 (249)

Hidden Solid-State Transformation of Darunavir in Low-Temperature Hot-Melt-Extruded Granules: Implications for Pharmacy Compounding and Routine Quality Control. [PDF]

Pharmaceutics
Mandrik M, Makarova V, Korol L, Sadkovskii I, Krasnyuk I, Antonov S.   +5 more
europepmc   +1 more source

Acute Effects of Acarbose and Canagliflozin, Alone and in Combination, on Postprandial GLP‐1 and Glycaemic Responses in Post‐Bariatric Hypoglycaemia: A Randomised Crossover Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To evaluate the acute effects of acarbose and canagliflozin, alone and in combination, on postprandial total GLP‐1 and glycaemic responses during a mixed meal test in adults with post‐bariatric hypoglycaemia (PBH). Materials and Methods This single‐centre, randomised, four‐period crossover physiological study included 12 adults with PBH ...
Wei Yang, Anna Kowalka, Lara Jimenez‐Pacheco, Veronica Greener, Kleopatra Alexiadou, Ahmed Ahmed, Julia Kenkre, Chioma Izzi‐Engbeaya, Saira Hameed, Harvinder Chahal, Bernard Khoo, Tricia M.‐M. Tan   +11 more
wiley   +1 more source

Modification patents across multiple NDAs in pharmaceutical protections. [PDF]

Health Aff Sch
Feldman R, Alsaffar R, Sakib T.
europepmc   +1 more source

Reduced Risk of MASLD and Cardiometabolic Disease Following Renal Denervation Therapy in Patients With Resistant Hypertension

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Introduction Autonomic dysfunction increases the risk of cardio‐kidney‐metabolic (CKM) syndrome including metabolic dysfunction‐associated steatotic liver disease (MASLD), type 2 diabetes (T2D), cardiovascular disease (CVD) and chronic kidney disease (CKD).
Alex E. Henney, Matthew Anson, David R. Riley, Laurent Fauchier, Joel P. Giblett, Gregory Y. H. Lip, Rayaz A. Malik, Daniel J. Cuthbertson, Uazman Alam   +8 more
wiley   +1 more source

Taurine-based Active Pharmaceutical Ingredient Ionic Liquids Modulate the Perifollicular Microenvironment for Androgenic Alopecia Treatment. [PDF]

Adv Healthc Mater
Yang L, Wang Y, Lei L, He B, Chen Y, Cao J.   +5 more
europepmc   +1 more source

Early Testing of a Mobile App‐Based Intervention to Support Body Weight Awareness and Monitoring in Pregnancy: A Randomised Controlled Feasibility Trial (BUMP2.0)

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To assess the feasibility of a mobile app‐based intervention to support gestational weight gain awareness and monitoring. Materials and Methods A total of 157 women aged ≥ 18 years, at < 20 weeks' gestation, were randomised 2:1 to an intervention (n = 107) or control group (n = 50), and followed‐up until late pregnancy (34 weeks ...
Moscho Michalopoulou, Stella J. P. Haffner, Susan A. Jebb, Lucy MacKillop, Yuan Chi, Nerys M. Astbury   +5 more
wiley   +1 more source

GLP‐1–Based Therapy in Type 1 Diabetes: Balancing Efficacy, Safety, and Patient Selection

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To critically examine the evolving evidence on glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and the dual glucose‐dependent insulinotropic polypeptide (GIP)/GLP‐1 receptor agonist tirzepatide as adjuncts to insulin therapy in type 1 diabetes (T1D), with particular emphasis on their benefit–risk balance in individuals with ...
Thales Rossatto, Ricardo de Andrade Oliveira, Andréia Machado Cardoso   +2 more
wiley   +1 more source

Developing a Method to Quantify Swelling Force Generated by the Osmotic Pump Tablet Push Layer. [PDF]

Pharmaceutics
Rogers TL, Robart S, Watson T, Wang R, Bernthal H, Ahmadi V.   +5 more
europepmc   +1 more source

The Smart MDI System in People With Type 1 Diabetes and High HBA1C: A Randomized Controlled Trial Demonstrating That Response to Alerts Drives Outcomes

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims The aim was to assess the efficacy and safety of the smart multiple daily injections (MDI) system versus MDI plus continuous glucose monitor (CGM) in people with Type 1 diabetes and HbA1c ≥ 8%. Material and Methods After a 3‐week run‐in, 143 participants were randomized to Smart MDI or MDI + CGM.
Laurent Crenier, Martin Haluzik, Marcus Lind, Pieter Gillard, Regis P. Radermecker, Angela Girelli, Jens Kroeger, Valeria Cosma, Francesco Giorgino, Charles Thivolet, Peter Adolfsson, Tobias Wiesner, Emmanuel Sonnet, Christophe de Block, Torben Biester, Helene Hanaire, Fabio di Piazza, Fabiona Hoevelaken, Renee Tillie, Tim van den Heuvel, Shannon Edd, Ohad Cohen   +21 more
wiley   +1 more source

Stability Study of a Frozen Oseltamivir 15 mg/mL Oral Solution in Amber Glass Bottles. [PDF]

Pharmaceutics
Ramirez JCR, Sáez AG, Madrid MEM, Viney AC, Herreros JMA, Rojo PA.   +5 more
europepmc   +1 more source