Results 171 to 180 of about 3,356,214 (292)

Stiffness‐Programmable Origami Robots With Tendon‐Driven Actuation via Multimaterial 3D Printing

open access: yesAdvanced Robotics Research, EarlyView.
Motion diversity is achieved in a tendon‐driven origami robot through programmable stiffness rather than modified actuation. Multimaterial 3D printing embeds soft creases, modular inserts redirect identical tendon inputs into distinct behaviors, and variable‐stiffness inserts enable real‐time switching.
Elisha Lerner, Jianguo Zhao
wiley   +1 more source

Flexible Sensors for Robotics Tactile Perception: A Review

open access: yesAdvanced Robotics Research, EarlyView.
Flexible tactile sensing for robotics is reviewed through four interconnected dimensions. Physical mechanisms include piezoresistive, capacitive, piezoelectric, triboelectric, iontronic, and optical sensing. Structural design includes bioinspired, defect‐based, and MEMS‐based tactile systems.
Yu Song, Ying Chen, Yihao Chen, Xue Feng
wiley   +1 more source

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

open access: yesAdvanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan   +17 more
wiley   +1 more source

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

open access: yesAdvanced Science, EarlyView.
When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source

Mechanotransduction and cell fate: from molecular sensors to multicellular self-organization. [PDF]

open access: yesFront Cell Dev Biol
Estrada Elorza MDC   +6 more
europepmc   +1 more source

Some stochastic comparisons in series systems with active redundancy

open access: yes
We compare the lifetimes of series systems with different allocations of active redundancy using a variety of stochastic comparisons. It is assumed that only one spare can be allocated to each component of the system.Reliability Series systems Active ...
Valdés, José E.   +3 more
core  

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen   +19 more
wiley   +1 more source

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