Results 61 to 70 of about 3,356,214 (292)
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Active fault-tolerance of the unmanned aerial vehicle automatic control systems
International Journal of Aviation, Aeronautics, and Aerospace, 2020 This paper presents an introductory overview of principles of the three-layer hierarchy of active fault-tolerance, providing, determination of the fault type with as many details as enough to get recoverable fault reason and failure toleration by ...
Vuong Anh Trung +4 more
doaj +1 more source
Exploiting redundancy in large materials datasets for efficient machine learning with less data
Nature Communications, 2023 Extensive efforts to gather materials data have largely overlooked potential data redundancy. In this study, we present evidence of a significant degree of redundancy across multiple large datasets for various material properties, by revealing that up to
Kangming Li +5 more
doaj +1 more source
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
FEBS Open Bio, EarlyView.Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source
Active Learning for Visual Image Classification Method Based on Transfer Learning
IEEE Access, 2018 The active learning method involves searching for the most informative unmarked samples by query function, submitting them to the expert function for marking, then using the samples to train the classification model in order to improve the accuracy of ...
Jihai Yang, Shijun Li, Wenning Xu
doaj +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
ANALYSIS OF RELIABILITY OF RESERVED AUTOMATIC CONTROL SYSTEMS OF INDUSTRIAL POWER PROCESSES
Известия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2014 This paper describes the comparative analysis of the main structural schemes for reserved automatic control and regulation devices of important objects of power supply with increased reliability requirements.
V. A. Anishchenko +2 more
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