Results 131 to 140 of about 6,781,062 (281)

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Blacks about to attack Leichardt's Camp, near the Gulf of Carpentaria, 1845 [picture] /

, 1890
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an9025855-4; Exhibited: "Mr. Gilbert's Beautiful Parrakeet", National Library of Australia Visitor Centre, 22 June - 14 October 2007 ...
Macfarlane, J., active 1890-1898.
core  

ATM-Dependent Recruitment of BRD7 is required for Transcriptional Repression and DNA Repair at DNA Breaks Flanking Transcriptional Active Regions. [PDF]

Adv Sci (Weinh), 2020
Hu K, Li Y, Wu W, Xie L, Yan H, Cai Y, Chen D, Jiang Q, Lin L, Chen Z, Liao JY, Zhang Y, Koeffler HP, Yin D, Song E.   +14 more
europepmc   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Sturt's party threatened by blacks at the junction of the Murray and Darling, 1830 [picture] /

, 1890
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an9025855 ...
Macfarlane, J., active 1890-1898.
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Captain Rossiter comes to Eyre's aid, Great Australian Bight, 1841 [picture] /

, 1890
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an9025855 ...
Macfarlane, J., active 1890-1898.
core  

First Insights into the Applicability and Importance of Different 3D Magnetic Field Extrapolation Approaches for Studying the Preeruptive Conditions of Solar Active Regions

The Astrophysical Journal
The three-dimensional (3D) coronal magnetic field has not yet been directly observed. However, for a better understanding and prediction of magnetically driven solar eruptions, 3D models of solar active regions are required.
Marianna B. Korsós, Robert Jarolim, Robertus Erdélyi, Astrid M. Veronig, Huw Morgan, Francesca Zuccarello   +5 more
doaj   +1 more source

Identifying Active Aging Policy Objectives in Italian Regions

Social Sciences
Background: In light of the main challenges recognized as being linked to the operationalization of the active aging concept at the policy level, the present study aimed to understand whether and to what extent Italian regional governments plan to deal ...
Davide Lucantoni, Giovanni Lamura, Marco Socci, Francesco Barbabella, Valerio Intraligi, Andrea Principi   +5 more
doaj   +1 more source