Results 51 to 60 of about 1,351,620 (240)

Properties of Flare-imminent versus Flare-quiet Active Regions from the Chromosphere through the Corona. I. Introduction of the AIA Active Region Patches (AARPs)

The Astrophysical Journal, 2023
We begin here a series of papers examining the chromospheric and coronal properties of solar active regions. This first paper describes an extensive data set of images from the Atmospheric Imaging Assembly on the Solar Dynamics Observatory curated for ...
Karin Dissauer, K. D. Leka, Eric L. Wagner   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Multi‐Wavelength Transformer‐Based 24‐Hour Solar Flare Forecasting at the Active‐Region Level

Space Weather
Solar flare forecasting remains challenging due to the complex spatiotemporal evolution of solar active regions (ARs) and the severe class imbalance associated with high‐impact events. In this work, we investigate a transformer‐based framework for active‐
Dunia Alatoom, Nikos Nikolaou
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Full-disk spectroscopy of the solar corona across a solar cycle with Hinode/EIS

Frontiers in Astronomy and Space Sciences
The structure and dynamics of the solar corona evolve with the Sun’s magnetic cycle, yet how this variability manifests in the disk-integrated, Sun-as-a-star observables used in stellar activity studies remains poorly constrained. We compile 18 full-disk
James McKevitt, James McKevitt, Ignacio Ugarte-Urra, Peter R. Young, Peter R. Young   +4 more
doaj   +1 more source

Cancellation analysis of current density in solar active region NOAA10019

Journal of Space Weather and Space Climate, 2015
Solar flares are often associated with changes in the fine magnetic structure of the emitting active region. Such topological modification results in variations of both the scaling properties of the fields’ fluctuations, and the fractal dimension of the ...
De Vita Gaetano, Vecchio Antonio, Sorriso-Valvo Luca, Briand Carine, Primavera Leonardo, Servidio Sergio, Lepreti Fabio, Carbone Vincenzo   +7 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source