Results 51 to 60 of about 6,770,206 (281)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The location and kinematics of the emission line regions in Active Galactic Nuclei [PDF]
, 2008 This thesis contains the results from a study of the optical emission lines of various samples of active galactic nuclei (AGN). We have used three separate techniques to determine the precise kinematics and the relative location of the emission line ...
Mullaney, J R, Mullaney, J.R.
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Deep Learning–based Solar Flare Forecasting Model. III. Extracting Precursors from EUV Images
The Astrophysical Journal Supplement Series, 2023 A solar flare is one of the most intense solar activities, and flare forecasting is necessary to avoid its destructive impact on the near-Earth space environment and technological infrastructure.
Dezhi Sun +3 more
doaj +1 more source
The onset and association of CMEs with sigmoidal active regions [PDF]
, 2000 Previous studies of active regions characterised by Soft X-ray S or inverse-S morphology [Canfield et al., 1999], have found these regions to possess a higher probability of eruption.
Harra, LK +3 more
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The Astrophysical Journal, 2023 We begin here a series of papers examining the chromospheric and coronal properties of solar active regions. This first paper describes an extensive data set of images from the Atmospheric Imaging Assembly on the Solar Dynamics Observatory curated for ...
Karin Dissauer +2 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Multi‐Wavelength Transformer‐Based 24‐Hour Solar Flare Forecasting at the Active‐Region Level
Space WeatherSolar flare forecasting remains challenging due to the complex spatiotemporal evolution of solar active regions (ARs) and the severe class imbalance associated with high‐impact events. In this work, we investigate a transformer‐based framework for active‐
Dunia Alatoom, Nikos Nikolaou
doaj +1 more source