Results 41 to 50 of about 828,248 (268)
A drug as a two-faced Janus: dose-effect, adverse events
Research Results in PharmacologyIntroduction: In the pharmaceutical industry, the 21st century was marked by the creation of new highly effective drugs: synthetic, immunobiological, genetic engineering, etc. Pharmacotherapy with highly effective drugs leads to a detailed study of their
Sofia Ya. Skachilova +5 more
doaj +1 more source
The safety profile of drotrecogin alfa (activated) [PDF]
Critical Care, 2007 Continued safety assessment is essential for any newly approved therapy. Drotrecogin alfa (activated; DrotAA), which is approved for use in severe sepsis, has undergone clinical trials with corresponding safety analyses since 1995. However, the only comprehensive review of all trials is that reported in 2003 by Bernard and coworkers.
FUMAGALLI, ROBERTO, Mignini, MA
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver‐facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note‐taking features to support ...
Micah A. Skeens +4 more
wiley +1 more source
Chemical Constituents, Neuroprotective and Antioxidant Potential of Klasea centauroides Leaves
Applied Sciences, 2023 Owing to progressive aging in the population, there is an increase in patients with cognitive impairment. For the prevention of dementia, the use of plant remedies is relevant. Of particular interest is Klasea centauroides (L.) Cass.
Yanina G. Razuvaeva +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source
Modern railways for the 21st century – a challenge not only for designers
Acta Polytechnica CTU Proceedings, 2022 The paper outlines the basic goals for modern rail transport in the Czech Republic. This contribution points out some challenges and technical tasks that project engineers and operators of the rail transport in the Czech Republic will have to deal with ...
Josef Kolář
doaj +1 more source
Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review
Pediatric Blood &Cancer, EarlyView.ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean +7 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Animal‐assisted activities (AAAs) with therapy dogs have shown positive effects on patient well‐being and quality of life in various areas of medicine, including pediatric oncology. However, research on this topic is limited. The aim of this study is to present the current status of AAA in pediatric oncology in Germany, Austria, and
Jan‐Marius Wedig +7 more
wiley +1 more source
Nihon Kikai Gakkai ronbunshu, 2014 Highway fatalities in Japan have been increasing over the past 3 years despite decline of traffic fatalities. Most of accidents on highway are caused by careless driving including drowsy driving. Therefore, a number of researches on detecting such drowsy
Shintaro SAIGO +2 more
doaj +1 more source
Research on Motor Speed Control Method Based on the Prevention of Vehicle Rollover
Energies, 2022 Vehicle driving safety is an important performance indicator for vehicles, and there is still much room for development in the active safety control of electric vehicles.
Fuhuai Jiang +3 more
doaj +1 more source