Results 51 to 60 of about 828,248 (268)

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

Multi-field Coupling Early Warning of Climate-induced Cascading Landslide Hazards: The Likan Landslides in the Upper Yellow River, China

International Journal of Applied Earth Observations and Geoinformation
Under a sustained warming climate, reservoir‐area landslides exhibit increasingly complex, non-linear interactions. The cascade “climate or seasonal variability-soil rheology-vegetation response/feedback-impulse-wave risk” constitutes an emerging safety ...
Zhenkui Gu, Peng Xin, Xin Yao, Shenghong Cao   +3 more
doaj   +1 more source

Characteristics of properties of carbohydrase enzyme complexes Bacillus subtilis strain [PDF]

BIO Web of Conferences
In this study, we have obtained two enzymes from the group of carbohydrases, cellulase and hemicellulase, secreted by vegetative cells of the B. subtilis strain, and comparatively characterized their properties in order to determine the possibility of ...
Mukhammadiev Rinat, Valiullin Lenar, Tarasova Evgenya, Mukhammadieva Alina, Saifullin Almaz, Yarullin Ainur, Karimullina Ilsiyar, Khusainov Ilnur, Mukhammadiev Rishat   +8 more
doaj   +1 more source

A Population‐Based Study on Childhood Aplastic Anemia—Incidence, Outcomes, and Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala, Riitta Niinimäki, Tytti Pokka, Anu Huurre, Liisa Järvelä, Sauli Palmu, Tuuli Pöyhönen, Pauliina Utriainen, Henri Aarnivala   +8 more
wiley   +1 more source

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas, Jakob Q. Weiss, Kellee N. Parker, Cathy Lee‐Miller   +3 more
wiley   +1 more source

Administering Blinatumomab via Continuous Intravenous Infusion in Pediatric Patients—A Single‐Institution Retrospective Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab, a CD19xCD3 bispecific T‐cell engager, has become standard therapy for children with de novo B‐cell acute lymphoblastic leukemia (B‐ALL). This retrospective review describes the experience of blinatumomab administration in pediatric patients.
Julia M. Hurley, Ryleigh Krueger, Kellie Joyce, James Stanley, Mary Waskerwitz‐Freyer, Marielle Klunder, David J. Hoogstra   +6 more
wiley   +1 more source

A review of safety test methods for new car assessment program in Southeast Asian countries

Open Engineering, 2023
Vehicles with advanced active safety technology can decrease the significant traffic accidents that can lead to death. This active safety frontier falls under primary safety in the European New Car Assessment Program (Euro NCAP) 2025 Roadmap, which has ...
Halimi Siti Nur Atiqah, Rasmana Susijanto Tri, Adiputra Dimas, Yahya Wira Jazair, Rahman Mohd Azizi Abdul, Ariff Mohd Hatta Mohammed, Husain Nurulakmar Abu, Kassim Khairil Anwar Abu   +7 more
doaj   +1 more source

THE INTELLIGENT SYSTEMS OF AUTOMOTIVE ACTIVE SAFETY

TRANSPORT, 2002
The subject of research is the idea of creation automobile systems of active safety basing on predictable use of potential possibilities of a wheel coupling with a road. Together with the generally accepted dependencies between the tire grip µ wheel slip, s, it is expedient to use potential µ-s-curves which can be deduced, having applied some ...
Ivanov, Valentin, Boutylin, Vladimir
openaire   +4 more sources

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Development characteristics and prediction model of the water-conducting fractured zone in typical mining-induced structural overburden in the mountainous areas of Southwestern China

Frontiers in Built Environment
IntroductionIn mining areas of the mountainous regions of Southwestern China, the overlying strata above goafs are mostly thick bedrock with well-developed structural planes. With large-scale exploitation of mineral resources, extensive water- conducting
Jun Li, Jun Li, Jiawei Wan, Jiawei Wan, Xiang Li, Xiang Li, Xingxing Du, Xingxing Du, Haoyuan Gao, Haoyuan Gao, Bin Li, Bin Li   +11 more
doaj   +1 more source