Results 81 to 90 of about 17,725,252 (297)

Associations between Screen Time and Physical Activity among Spanish Adolescents

PLoS ONE, 2011
Excessive time in front of a single or several screens could explain a displacement of physical activity. The present study aimed at determining whether screen-time is associated with a reduced level of moderate to vigorous physical activity (MVPA) in Spanish adolescents living in favorable environmental conditions.A multi-stage stratified random ...
Jose A Serrano-Sanchez, Sara Martí-Trujillo, Angela Lera-Navarro, Cecilia Dorado-García, Juan J González-Henríquez, Joaquín Sanchís-Moysi   +5 more
openaire   +5 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Mothers’ and father’s perceptions of the risks and benefits of screen time and physical activity during early childhood: a qualitative study

BMC Public Health, 2018
Background This study sought to explore mothers’ and fathers’ perceptions of the risks and benefits of screen time and active play during early childhood.
Trina Hinkley, Jennifer R. McCann
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

How Children Use Active Videogames and the Association Between Screen Time and Physical Activity [PDF]

Games for Health Journal, 2015
The energy required to play active videogames (AVGs) has been reported on in the literature; however, little is known about how children use such games in their home environment. The aim of this study was to investigate children's use of AVGs and the association among AVG use, other screen-based activities, and physical activity levels.Eight hundred ...
Hussey, Juliette, Forde, Cuisle
openaire   +4 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diet, physical activity, and screen time among school students in Manipur

Indian Journal of Community Medicine, 2019
Adolescence is a critical time in the development of lifelong healthy eating and exercise habits. The high prevalence of adolescents exposed to excessive screen time is a matter of concern because of its association with several health problems, such as overweight and obesity, alterations in blood glucose and cholesterol, poor school performance ...
Markordor Lyngdoh, Brogen Singh Akoijam, R K S. Agui, K h Sonarjit Singh   +3 more
openaire   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Leisure Activities to Reduce Screen Time

Dinamisia : Jurnal Pengabdian Kepada Masyarakat
This community service initiative was developed in response to the rising prevalence of screen-based activities among children during school holidays, which adversely affect their physical, cognitive, and social development. The program targeted Madrasah Ibtidaiyah students in Sleman, Yogyakarta, aiming to provide productive leisure-time alternatives ...
openaire   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source