Results 171 to 180 of about 4,321,073 (342)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Controlled dynamic remodeling of the spliceosome active site enables the first step of splicing. [PDF]

Proc Natl Acad Sci U S A
Martino G, Manigrasso J, La Sala G, Marcia M, De Vivo M.   +4 more
europepmc   +1 more source

Dual-active-site engineering via orbital modulation of Fe single atoms on defective TiO ₂ for enhanced photocatalytic NO removal [PDF]

Huan Shang, Yue He, Qing Wang, Hongbao Jia, Jiale Wang, Haifeng Zhao, Xinwang Chen, Xinyu Deng, Ziyan Zhang, Shuwei Gu, Jue Wu, Jian Zhu, Guisheng Li, Hexing Li, Dieqing Zhang   +14 more
openalex   +1 more source

Structure of recombinantLeishmania donovanipteridine reductase reveals a disordered active site [PDF]

, 2010
K.L. Barrack, L.B. Tulloch, Lynsey-Ann Burke, Paul K. Fyfe, William N. Hunter   +4 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Crystal structure of apo human spermidine synthase reveals dynamic rearrangement at the active site. [PDF]

Struct Dyn
Fagbohun OO, Canfield MA, Clinger JA.
europepmc   +1 more source

2D interaction of compound 6e (left) and indomethacin drug (right) within the active site of cyclooxygenase-1 (COX-1) (PDB ID: 1EQG).

Yasser Hussein Issa Mohammed (17140711), Ahmed Hassen Shntaif (22320292), Saad Alghamdi (362506), Ahd A. Mansour (21660692), Naeem F. Qusty (15416890), Azhar S. Sindi (13259916), Ahmad O. Babalghith (15279713), Ghazi A. Bamagous (22320295), Eman Adnan Abu-Seer (22320298)   +8 more
openalex   +1 more source

Active-site zinc ligands and activated H2O of zinc enzymes.

, 1990
B L Vallee, David S. Auld
openalex   +2 more sources

Solution studies of copper(II) complexes as a contribution to the study of the active site of galactose oxidase [PDF]

, 2004
Stela Maris de Moraes Romanowski, F. V. Tormena, Viviane A. dos Santos, M. Hermann, A.S. Mangrich   +4 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source