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Mechanism of glutathionylation of the active site thiols of peroxiredoxin 2. [PDF]
Peskin AV +5 more
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σ-π dative bond stabilizing copper active site drives CO<sub>2</sub> electrocatalysis to hydrocarbon. [PDF]
Qian Z +14 more
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Active site determinants of yeast Pah1 phosphatidate phosphatase activity and cellular functions. [PDF]
Stukey GJ +5 more
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Corrigendum to "KEAP1 C151 active site catalysis drives electrophilic signaling to upregulate cytoprotective enzyme expression" [Redox Biology 88 (2025) 103906]. [PDF]
Schnell MR +9 more
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Crystal structures of Salmonella enterica FraB deglycase reveal a conformational heterodimer with remarkable structural plasticity at the active site. [PDF]
Zakharova K +6 more
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Peroxidase Active Site Activity Assay
2010Cyclooxygenase enzymes house spatially distinct cyclooxygenase- and peroxidase-active sites. The two-electron reduction of peroxides to their corresponding alcohols by the heme bound in the peroxidase-active site converts the heme to a ferryloxoprotoporyphrin cation radical, with a reductant providing the two electrons necessary to bring the heme back ...
Kelsey C, Duggan +2 more
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Thrombin active site inhibitors
Bioorganic & Medicinal Chemistry, 1995Development of small molecule thrombin active site inhibitors has been an area of intense research. A brief review on recent progress and challenges is outlined.
J, Das, S D, Kimball
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Seminars in Thrombosis and Hemostasis, 1986
Knowledge is being gained about topographic features of alpha-thrombin and how they may define thrombin specificity and biologic functions. Thrombin is not just an enzyme with moderately restricted proteolytic capabilities, yet with extraordinarily high specificities for certain bonds (such as the A alpha-cleavage site in fibrinogen), but also is a ...
J W, Fenton, D H, Bing
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Knowledge is being gained about topographic features of alpha-thrombin and how they may define thrombin specificity and biologic functions. Thrombin is not just an enzyme with moderately restricted proteolytic capabilities, yet with extraordinarily high specificities for certain bonds (such as the A alpha-cleavage site in fibrinogen), but also is a ...
J W, Fenton, D H, Bing
openaire +2 more sources

