Results 241 to 250 of about 4,321,073 (342)

Active site determinants of yeast Pah1 phosphatidate phosphatase activity and cellular functions. [PDF]

J Biol Chem
Stukey GJ, Sharma PK, Jog R, Kwiatek JM, Han GS, Carman GM.   +5 more
europepmc   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Crystal structures of Salmonella enterica FraB deglycase reveal a conformational heterodimer with remarkable structural plasticity at the active site. [PDF]

Protein Sci
Zakharova K, Law JD, Gao Y, Kovvali S, Wysocki VH, Gopalan V, Bell CE.   +6 more
europepmc   +1 more source

Jack bean (Canavalia ensiformis) urease. Probing acid–base groups of the active site by pH variation

, 2005
Barbara Krajewska, Stefano Ciurli
openalex   +2 more sources

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Mechanism of glutathionylation of the active site thiols of peroxiredoxin 2. [PDF]

J Biol Chem
Peskin AV, Meotti FC, Magon NJ, de Souza LF, Salvador A, Winterbourn CC.   +5 more
europepmc   +1 more source

The Histamine N-Methyltransferase T105I Polymorphism Affects Active Site Structure and Dynamics

, 2007
Karen Rutherford, Walther Parson, Valerie Daggett   +2 more
openalex   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Revisiting Active Site Quantification in CO₂ Electroreduction: The Case for CO Displacement. [PDF]

ACS Energy Lett
Zhou Y, Bowers B, Bagger A, Yang G, Steier L, Ryan MP, Stephens IEL.   +6 more
europepmc   +1 more source

A comprehensive design of stable aldol reaction catalysts by tuning active site, support, and solvent properties

, 2019
Anton De Vylder
openalex   +1 more source