Results 301 to 310 of about 11,841,496 (406)

A combinatorially complete epistatic fitness landscape in an enzyme active site. [PDF]

Proc Natl Acad Sci U S A
Johnston KE, Almhjell PJ, Watkins-Dulaney EJ, Liu G, Porter NJ, Yang J, Arnold FH.   +6 more
europepmc   +1 more source

The Nucleus as a Site of Biochemical Activity

Cold Spring Harbor Symposia on Quantitative Biology, 1956
V. G. Allfrey, Syozo Osawa, Alfred E. Mirsky   +2 more
openaire   +3 more sources

Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins

FEBS Open Bio, EarlyView.
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet, Julia Bartoli, Atakan Kabtan, Chloé M. Piras, Audrey C. Tempier, Eric Cascales, Julie P. Viala   +6 more
wiley   +1 more source

Cofactor binding triggers rapid conformational remodelling of the active site of a methyltransferase ribozyme. [PDF]

J Biol Chem
Jiang H, Liu G, Gao Y, Gan J, Chen D, Murchie AIH.   +5 more
europepmc   +1 more source

KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca2+‐mediated response to dimethylsulfoxide (DMSO)

FEBS Open Bio, EarlyView.
Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu, Lavinia Liliana Ruta, Claudia Valentina Popa, Simona Ghenea, Ileana Cornelia Farcasanu   +4 more
wiley   +1 more source

The Trajectory of Damaged-Base Eversion into the Active Site of Apurinic/Apyrimidinic Endonuclease APE1 Regulates This Enzyme's Substrate Specificity. [PDF]

Int J Mol Sci
Bulygin AA, Kuznetsov NA.
europepmc   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Computational studies on the catalytic potential of the double active site for enzyme engineering. [PDF]

Sci Rep
Krishna NB, Roopa L, Pravin Kumar R, S GT.   +3 more
europepmc   +1 more source

The sequence of a peptide containing the active site phosphohistidine residue of phosphoglycerate mutase from chicken breast muscle.

, 1975
Z.B. Rose, Naotaka Hamasaki, Sukoluhle Dube   +2 more
openalex   +1 more source