Results 251 to 260 of about 11,761,461 (345)

Comprehensive study of imidazole-based hydrazones: From design, synthesis, and characterization to in vitro and in silico antiproliferative activity analysis. [PDF]

Turk J Chem
Dilek Ö.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Polysaccharides from sea buckthorn - Ultrasound-assisted enzymatic extraction, purification, structural characterization, and antioxidant activity analysis. [PDF]

Food Chem X
Wen J, Huang R, Li S, Jiang L, Shao L, Zhang Q, Shan C.   +6 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

High-throughput markerless pose estimation and home-cage activity analysis of tree shrew using deep learning. [PDF]

Animal Model Exp Med
Wang Y, Su F, Cong R, Liu M, Shan K, Li X, Zhu D, Wei Y, Dai J, Zhang C, Tian Y.   +10 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Analysis of Early Childhood Play Activities in Indonesia

Desvi Wahyuni, Mona Ardina, Rahmah Novianti, Vivi Patra Komala, Arnita Fitri   +4 more
openalex   +2 more sources

Land suitability analysis to assess the potential of public open spaces for urban agriculture activities

, 2020
Maicol Fernando Camargo Hernández
openalex   +1 more source

Gene expression and enzyme activity analysis of carbohydrate digestion in Strongylocentrotus purpuratus larvae.

J Exp Biol
Hildebrand J, Stumpp M.
europepmc   +1 more source