Results 111 to 120 of about 18,332,721 (387)

Learning Activity Spaces: Towards Flexibility in Learning Design?

open access: yes2009 Ninth IEEE International Conference on Advanced Learning Technologies, 2009
Designing a computer-supported learning scenario involving a constructivist approach of learning lays on a paradox. On the one hand, learning flows must be precisely described - including role distribution, required resources, tools, and scaffolds - to be realized in computer-supported environments.
Lejeune, Anne   +7 more
openaire   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Comparative Study of the Single‐Event Functional Interrupt (SEFI) Rate in Solid‐State Drives (SSD) Through Ground and On‐Orbit Testing

open access: yesSpace Weather
Space radiation poses a significant threat to the reliability of spacecraft equipment, while traditional static space environment models exhibit substantial inaccuracies in calculating on‐orbit error rates. This study investigates single‐event functional
Yingqi Ma   +12 more
doaj   +1 more source

Research on Removing Thin Cloud Interference in Solar Flare Monitoring with SMAT-Configured Telescopes

open access: yesUniverse
The precise monitoring of solar flares holds significant scientific value for space mission safety, communication security, and space environment forecasting.
Hongyan Li   +3 more
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Topological Schemas of Memory Spaces

open access: yes, 2017
Hippocampal cognitive map---a neuronal representation of the spatial environment---is broadly discussed in the computational neuroscience literature for decades.
Babichev, Andrey, Dabaghian, Yuri
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Martian Ionospheric Cold Hydrogen Ion Escape at Solar Maximum: First Observations

open access: yesThe Astrophysical Journal
The water escape from Mars to space could be in the form of hydrogen and oxygen ions as driven by solar wind–Mars interactions. Although oxygen ion escape has been extensively investigated, the H ^+ escape rate was measured only at solar minimum.
Qi Xu   +10 more
doaj   +1 more source

On the wings of a dream: The Space Shuttle [PDF]

open access: yes
Described are the organization and some of the interests and missions of NASA, the Space Transportation System, the Space Shuttle orbiter Enterprise, astronaut training and clothing, being launched into space, living and working in weightlessness ...

core   +1 more source

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