Results 121 to 130 of about 18,332,721 (387)

Can a Spacecraft Use Solar Panels at Saturn? [PDF]

, 2001
This hands-on activity is designed to introduce students to the complexities of using solar panels in space exploration.

core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Relationship Between Recurrent Magnetic Flux Rope and Moving Magnetic Features

Universe
Large-scale magnetic flux ropes (MFRs) usually become visible during an eruption and are the core structures of coronal mass ejections, but the nature of MFRs is still a mystery. Here, we identify a large transequatorial MFR that spans across NOAA 13373 (
Yin Zhang, Jihong Liu, Quan Wang, Suo Liu, Jing Huang, Jie Chen, Baolin Tan   +6 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

IonoGAN: An Enhanced Model for Forecasting Quiet and Disturbed Ionospheric Features From Predicted Ionograms

Space Weather
Ionograms are radar echo graphs that depict vertical ionospheric density profiles, structures, fluctuations, and irregularities, with the F region represented by F‐trace and Spread‐F features in the graphs.
Chu Qiu, Jinhui Cai, Zheng Wang, Pengdong Gao, Guojun Wang, Quan Qi, Bo Wang, Zhengwei Cheng, Jiankui Shi, Yajun Zhu, Xiao Wang, Kai Ding   +11 more
doaj   +1 more source

Dynamic X-ray imaging of the magnetosheath expected during a super storm

Frontiers in Astronomy and Space Sciences
The Earth’s magnetosheath is a vital source region of soft X-ray emissions generated by the solar wind charge exchange (SWCX) mechanism in geospace.
Yuqi Gong, Yuqi Gong, Tianran Sun, Binbin Tang, Yihong Guo, Steve Sembay, Chi Wang, Chi Wang   +7 more
doaj   +1 more source

Development and validation of a ground-based Asymmetric Spatial Heterodyne Spectroscopy (ASHS) system for sounding neutral wind in the mesopause [PDF]

Atmospheric Measurement Techniques
Winds in the mesopause region are key to understanding atmospheric dynamics. This study presents a novel ground-based Asymmetric Spatial Heterodyne Spectroscopy (ASHS) system designed to measure these winds by observing the nighttime green line airglow ...
G. Zhu, G. Zhu, Y. Zhu, Y. Zhu, Y. Zhu, M. Kaufmann, T. Wang, T. Wang, T. Wang, W. Liu, W. Liu, W. Yuan, W. Yuan, S. Liu, S. Liu, G. Yang, G. Yang, G. Yang, J. Xu, J. Xu, J. Xu   +20 more
doaj   +1 more source

Cosmic Survey: What are Your Ideas About the Universe? [PDF]

, 2003
This product contains lesson plans and an activity composed of a three-part questionnaire that launches students on discussions about where objects in space are located, and when they were formed, as well as an introduction to the concepts of structure ...

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The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

The space station: Human factors and productivity [PDF]

Human factor researchers and engineers are making inputs into the early stages of the design of the Space Station to improve both the quality of life and work on-orbit.
Burns, M. J., Gillan, D. J., Nicodemus, C. L., Smith, R. L.   +3 more
core   +1 more source