Results 131 to 140 of about 17,989,902 (389)

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Automated Plasma Region Classification and Boundary Layer Identification Using Machine Learning

Remote Sensing
The accurate classification of plasma regions is a critical challenge in space science, with identifying dynamic boundary layers (BLs) being particularly complex.
Jiye Wang, Xuan Liu, Fanzhuo Dai, Rui Zheng, Yuanlin Han, Yang Wang, Andi Liu, Xinhua Wei, Lingqian Zhang, Hui Li, Chi Wang, Tieyan Wang, James L. Burch, Wolfgang Baumjohann   +13 more
doaj   +1 more source

Space Weather Activities in Ireland

, 2014
Talk on Irish space weather activities at workshop on geomagnetically induced currents, 5-6 March 2014, British Geological Survey, Edinburgh, UK (https://twiki.ukssdc.ac.uk/twiki/bin/view/SEREN/FirstMeeting).
openaire   +2 more sources

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Ice nucleus activity measurements of solid rocket motor exhaust particles [PDF]

The ice Nucleus activity of exhaust particles generated from combustion of Space Shuttle propellant in small rocket motors has been measured. The activity at -20 C was substantially lower than that of aerosols generated by unpressurized combustion of ...
Keller, V. W.
core   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

A novel mechanism for energy activation in biomolecules [PDF]

arXiv, 2020
An activated process consists of energy activation and barrier crossing; the former is a prerequisite for the latter. Barrier crossing has been studied extensively, but energy activation has been overlooked due to a lack of means to gauge its progress.
arxiv  

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source

The Role of Magnetic Skeleton in Solar Flare Filaments Activity

The Astrophysical Journal
We report an M9.3 flare and filaments activities from NOAA Active Region 11261 that are strongly modulated by the 3D magnetic skeleton. Magnetic field extrapolation from the vector magnetic field suggests complex magnetic connectivity and the existence ...
Juan Guo, Huaning Wang, Jingxiu Wang, Xiaoshuai Zhu, Jing Huang, Shanqiang Chen, Bingxian Luo, Siqing Liu, Yuanyong Deng, Jiaben Lin   +9 more
doaj   +1 more source

Chirality, anisotropic viscosity and elastic anisotropy in three-dimensional active nematic turbulence [PDF]

Commun Phys 7, 222 (2024)
Various active materials exhibit strong spatio-temporal variability of their orientational order known as active turbulence, characterised by irregular and chaotic motion of topological defects, including colloidal suspensions, biofilaments, and bacterial colonies.In particular in three dimensions, it has not yet been explored how active turbulence ...
arxiv   +1 more source