Results 141 to 150 of about 16,937,312 (352)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Gendered activity spaces: trends over three decades in Germany

open access: diamond, 2011
Joachim Scheiner   +2 more
openalex   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Contribution of magnetotail currents to Dst index during different intensity magnetic storms: a global MHD model study

open access: yesFrontiers in Astronomy and Space Sciences
The Disturbance Storm Time (Dst) index serves as a critical indicator for quantifying geomagnetic storm intensity; however, the precise contribution of magnetotail currents to its formation remains inadequately characterized.
Jiawen Yue   +6 more
doaj   +1 more source

Sustainable bioplastics manufacturing from renewable sources

open access: yesFEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto   +6 more
wiley   +1 more source

A Deep Learning-Enabled Ionogram Dataset for Detection and Classification of Low-latitude Spread-F Phenomena

open access: yesScientific Data
Research on the ionospheric Spread-F (SF) phenomenon holds significant value in both fields as ionospheric electrodynamic research and enhanced operational applications in radio-based technologies (e.g., communication and navigation).
Pengdong Gao   +12 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Application of a Grid-constrained U-shaped Neural Operator in Real-time Solar Corona Magnetic Field Extrapolation

open access: yesThe Astrophysical Journal Supplement Series
In this study, we propose a neural network framework, called the Grid-constrained U-shaped Neural Operator (GC-UNO), for real-time extrapolation of the coronal magnetic fields of active regions (ARs).
Hao Yang   +9 more
doaj   +1 more source

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