Results 61 to 70 of about 3,931,453 (288)

Theory of active chromatin remodeling [PDF]

open access: yesPhysical Review Letters, 2019
Nucleosome positioning controls the accessible regions of chromatin and plays essential roles in DNA-templated processes. ATP driven remodeling enzymes are known to be crucial for its establishment in vivo, but their non-equilibrium nature has hindered the development of a unified theoretical framework for nucleosome positioning.
Jiang, Zhongling, Zhang, Bin
openaire   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Where Theory meets Practice: A Case for an Activity Theory based Methodology to guide Computer System Design [PDF]

open access: yes, 2001
Computer system developers are increasingly being challenged to develop tools that are not only usable, but more importantly useful in the sense of assisting the user to achieve desired goals. This requirement has highlighted the importance of accounting
Mwanza, Daisy
core  

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Polar branches of stellar activity waves: dynamo models and observations

open access: yes, 2011
[Abridged abstract:] Stellar activity data provide evidence of activity wave branches propagating polewards rather than equatorwards (the solar case). Stellar dynamo theory allows polewards propagating dynamo waves for certain governing parameters.
A. F. Lanza   +56 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Identifying health and wellbeing related information management activities and needs in families with young children

open access: yesFinnish Journal of eHealth and eWelfare, 2012
Understanding how families manage health and wellbeing related information in their everyday lives is important in the user-centric design of information and communication technology (ICT) supported services.
Marilla Palmén   +2 more
doaj  

Conceptions Connected to Early Academic Studies in Computer Science: Focusing on Students, Lecturers, and Parents

open access: yesEducation Sciences
The goal of this study was to identify conceptions towards early academic studies in computer science. We focus on a program which offers high school students the unique opportunity to earn a B.Sc.
Lior Miller-Markovitz   +3 more
doaj   +1 more source

Magnetic Helicity Evolution During the Solar Activity Cycle: Observations and Dynamo Theory

open access: yes, 2003
We study a simple model for the solar dynamo in the framework of the Parker migratory dynamo, with a nonlinear dynamo saturation mechanism based on magnetic helicity conservation arguments.
Abramenko   +55 more
core   +1 more source

Cognitive Science and Psychology [PDF]

open access: yes, 1994
The protocol algorithm abstracted from a human cognizer's own narrative in the course of doing a cognitive task is an explanation of the corresponding mental activity in Pylyshyn's (1984) virtual machine model of mind.
Chow, Dr Siu L.
core   +1 more source

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