Results 41 to 50 of about 359,175 (254)

A midrange theory of local cross-sector action based on the actor-network theory

open access: yesSSM: Qualitative Research in Health, 2022
Given the value of cross-sector collaborations in solving complex societal problems, experts are now recommending that research focus on documenting process–effect linkages.
Angèle Bilodeau   +5 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Development of a successful microfinancing system: Actor-network theory perspective

open access: yesManagement : Journal of Contemporary Management Issues, 2019
The article aims to answer the following research question: “How were actors mobilized to form a network for promoting microfinancing system in a transforming country?”.
Halina Waniak-Michalak, Jan Michalak
doaj   +1 more source

An actor-network theory (ANT) approach to Turkish e-government gateway initiative [PDF]

open access: yes, 2009
There are various models proposed in the literature to analyze trajectories of e-Government projects in terms of success and failure. Yet, only the Actor-Network Theory (ANT) perspective (Heeks and Stanforth, 2007) considers the interaction factors among
Aykac, D. Selcen O.   +4 more
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Posłuszne klucze, chodliwe aparaty [PDF]

open access: yesAvant, 2013
The authors' commentary on Bruno Latour's "Technology is society made durable" provides the reader with an opportunity to become acquainted with actor-network theory.
Łukasz Afeltowicz, Witold Wachowski
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Network Theory| Networks, Societies, Spheres: Reflections of an Actor-network Theorist

open access: yesInternational Journal of Communication, 2011
In one way or another, we are all in this room responsible for having given to the notion of network an immense, and some could say, a hegemonic extension.
Bruno Latour
doaj   +2 more sources

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