Results 51 to 60 of about 262,464 (143)

Two sides of one coin: massive hepatic necrosis and progenitor cell-mediated regeneration in acute liver failure

Frontiers in Physiology, 2015
Massive hepatic necrosis is a key event underlying acute liver failure, a serious clinical syndrome with high mortality. Massive hepatic necrosis in acute liver failure has unique pathophysiological characteristics including extremely rapid parenchymal ...
Honglei eWeng, Xiaobo eCai, Xiaodong eYuan, Roman eLiebe, Steven eDooley, Hai eLi, Tai-Ling eWang   +6 more
doaj   +1 more source

Artificial liver support systems: what is new over the last decade?

Annals of Intensive Care, 2018
The liver is a complex organ that performs vital functions of synthesis, heat production, detoxification and regulation; its failure carries a highly critical risk.
Juan José García Martínez, Karim Bendjelid   +1 more
doaj   +1 more source

Liver transplantation for acute-on-chronic liver failure

The Lancet Gastroenterology & Hepatology
Acute-on-chronic liver failure (ACLF) occurs in the context of advanced liver disease and is associated with hepatic and extrahepatic organ failure, eventually leading to a major risk of short-term mortality. To date, there are very few effective therapeutic options for ACLF.
Artru, Florent, Trovato, Francesca, Morrison, Maura, Bernal, William, Mcphail, Mark   +4 more
openaire   +4 more sources

Liver transplantation for critically ill patients with acute on chronic liver failure: a prospective national programme of waitlist prioritisationResearch in context

The Lancet Regional Health. Europe
Summary: Background: Acute on Chronic Liver Failure (ACLF) complicates chronic liver disease (CLD) combining rapidly progressive hepatic with extra-hepatic multiple organ failure and high short-term mortality.
William Bernal, Rhiannon Taylor, Ian A. Rowe, Abhishek Chauhan, Matthew J. Armstrong, Michael E.D. Allison, Gwilym Webb, Tasneem Pirani, Joanna Moore, Laura Burke, Steven Masson, David Cressy, Brian J. Hogan, Rachel Westbrook, Rajiv Jalan, Kenneth J. Simpson, John Isaac, Douglas Thorburn   +17 more
doaj   +1 more source

The efficacy and safety of methylprednisolone in hepatitis B virus-related acute-on-chronic liver failure: a prospective multi-center clinical trial

BMC Medicine, 2020
Background Hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) is a severe condition with high mortality due to lack of efficient therapy. Until now, the use of methylprednisolone (MP) in HBV-ACLF is still controversial.
Lin Jia, Ran Xue, Yueke Zhu, Juan Zhao, Juan Li, Wei-Ping He, Xiao-Mei Wang, Zhong-Hui Duan, Mei-Xin Ren, Hai-Xia Liu, Hui-Chun Xing, Qing-Hua Meng   +11 more
doaj   +1 more source

Study of the Expression of Inflammatory Factors IL-4, IL-6, IL-10, and IL-17 in Liver Failure Complicated by Coagulation Dysfunction and Sepsis

Journal of Inflammation Research, 2021
Lei Li,1,* Ling Chen,1,* Fang Lin,2 Jinsong Mu,2 Dan Wang,1 Wei Zhang,1 Lai Mi,1 Yuling Qin,1 Yuesu Zhou1 1Department of Emergency, Fifth Medical Center of Chinese PLA Hospital, Beijing, 100039, People’s Republic of China; 2Department of Critical ...
Li L, Chen L, Lin F, Mu J, Wang D, Zhang W, Mi L, Qin Y, Zhou Y   +8 more
doaj  

Acute on chronic liver failure in cirrhosis [PDF]

Clinical and Molecular Hepatology, 2022
Marta Tonon, Salvatore Piano
doaj   +1 more source

Clinical and Genetic Profile of Pediatric and Adult Wilson's Disease in India

Gastro Hep Advances
Background and Aims: Wilson's disease (WD) is a disorder of copper metabolism caused by a mutation in the ATP7B gene. We aimed to comprehensively evaluate the clinical and genetic profiles of patients with WD.
Anand V. Kulkarni, Govardhan Bale, Ravikanth Vishnubotla, Anuhya Rambhatla, Mithun Sharma, Swapnali Sabhapandit, Archana Chintam, Manasa Alla, Shantan Venishetty, Sowmya Iyengar, Ravi Babu Komalla, Sumana Kolar Ramachandran, Balachandran Menon, Rakesh Kalapala, Rajesh Gupta, Padaki Nagaraj Rao, Duvvur Nageshwar Reddy, Michael L. Schilsky, K.Rajender Reddy   +18 more
doaj   +1 more source

Acute (Not Decompensation)-on-Chronic Liver Failure

GE: Portuguese Journal of Gastroenterology, 2017
Cilénia Baldaia
doaj   +1 more source

Etiology, clinical features, and outcomes in acute-on-chronic liver failure patients in the intensive care unit of a quaternary care center

Journal of Shalamar Medical & Dental College
Background: Multi-organ failure and a sharp decline in liver function are hallmarks of acute-on-chronic liver failure (ACLF), carrying high mortality. Objective: To determine the etiology, clinical presentations, and the mortality outcome in patients ...
Saleem Sharieff, Fariha Khan, Wajid Ali Rafai, Arslan Saleem Chughtai, Burhan Ahmed, Umar Farooq   +5 more
doaj   +1 more source