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Acute phase reaction and acute phase proteins [PDF]
Journal of Zhejiang University-SCIENCE B, 2005 A review of the systemic acute phase reaction with major cytokines involved, and the hepatic metabolic changes, negative and positive acute phase proteins (APPs) with function and associated pathology is given. It appears that APPs represent appropriate analytes for assessment of animal health.
Theodoor Niewold +3 more
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CD14 Is an Acute-Phase Protein [PDF]
The Journal of Immunology, 2004 Abstract The origin of soluble CD14 (sCD14) in the circulation is uncertain. To examine whether CD14 could be an acute-phase protein (APP), the levels of sCD14, IL-6, and C-reactive protein were determined by ELISA in serum and synovial fluid (SF) of patients with various arthropathies, and the regulation of CD14 synthesis was examined ...
Sylvette Bas +4 more
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Acute phase proteins in cats [PDF]
Ciência Rural, 2019 ABSTRACT: Acute phase proteins (APP) are proteins synthesized and released largely by hepatocytes upon the occurrence of cell damage or invasion by microorganisms. This article reviews the use of APP in feline diseases, identifying their usefulness in the clinical setting, analyzing 55 published papers.
Rita Mourão Rosa +1 more
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Angiotensinogen: an acute-phase protein? [PDF]
Hypertension, 1994 Angiotensinogen has been assumed to be an acute-phase protein, because some forms of acute inflammation, eg, the injection of lipopolysaccharide or cellite or partial hepatectomy, increased the hepatic synthesis of angiotensinogen. In addition, the well-characterized nephrectomy-induced stimulation of angiotensinogen was thought to represent an acute ...
M Soden +3 more
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Acute Phase Protein Response in Goats [PDF]
Journal of Veterinary Diagnostic Investigation, 2008 Acute phase proteins (APPs) are important diagnostic indicators of inflammatory disturbances in animals. The objectives of the current study were to validate analytical methods for measuring haptoglobin (Hp), serum amyloid A (SAA), acid soluble glycoprotein (ASG), fibrinogen, and albumin concentrations in goats and to evaluate their response to an ...
González, Félix H.D. +5 more
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Identification of a New Acute Phase Protein [PDF]
Journal of Biological Chemistry, 1995 We have previously reported mouse SIP24 protein as a secreted inducible protein produced by quiescent Balb/c 3T3 cells. SIP24 can be produced in response to many factors, including serum, basic fibroblast growth factor, prostaglandin F2 alpha, phorbol ester, and dexamethasone.
Quan-Sheng Liu, Marit Nilsen-Hamilton
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Acute-phase proteins: As diagnostic tool
Journal of Pharmacy And Bioallied Sciences, 2011 The varied reactions of the host to infection, inflammation, or trauma are collectively known as the acute-phase response and encompass a wide range of pathophysiological responses such as pyrexia, leukocytosis, hormone alterations, and muscle protein depletion combining to minimize tissue damage while enhancing the repair process.
Sachin Jain, Sania Naseem, Vidhi Gautam
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Acute-phase proteins in osteoarthritis
Seminars in Arthritis and Rheumatism, 1995 The joint destruction of osteoarthritis (OA) comprises loss of articular cartilage resulting from an imbalance of enzyme-catalized cartilage breakdown and regeneration. OA is thought to derive from defective chondrocyte metabolism and thus to inherently lack the large-scale systemic response that is the hallmark of rheumatoid arthritis (RA). Because of
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Acute Phase Proteins in Animals
, 2012 Acute phase proteins (APP) were first identified in the early 1900s as early reactants to infectious disease. They are now understood to be an integral part of the acute phase response (APR) which is the cornerstone of innate immunity. APP have been shown to be valuable biomarkers as increases can occur with inflammation, infection, neoplasia, stress ...
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Acute Phase Proteins as Cancer Biomarkers [PDF]
, 2011 Interactions between tumor cells and the host microenvironment have been shown to play a significant role in the initiation, progression, and invasiveness of human cancer. The complex changes in the tumor microenvironment have been shown to modulate the activation of the different arms of the host immune system including the acute phase response. Acute
Linda H. Malkas +3 more
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