Results 101 to 110 of about 975,400 (335)

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Redemptive benefit of atorvastatin in the risk factors of coronary artery disease [PDF]

, 2011
Cardiovascular disease, in particular coronary artery disease (CAD), is the principal cause of mortality in developed countries. The classical acute phase protein, C-reactive protein (CRP) is an exquisitely sensitive systemic marker of disease ...
Jayaraman Gowri , Arumugam Vijaya Anand , Shanmugam Achiraman , Govindha Raj Archunan , Subramaniyam Kalavathy , Palanisamy Sampath Kumar , Kalaiyarasan Vijaya Kumar Int J Cur Biomed Phar Res.
core  

Physiological responses of reared sea bream (Sparus aurata Linnaeus, 1758) to an Amyloodinium ocellatum outbreak [PDF]

, 2017
Amyloodiniosis represents a major bottleneck for semi-intensive aquaculture production in Southern Europe, causing extremely high mortalities. Amyloodinium ocellatum is a parasitic dinoflagellate that can infest almost all fish, crustacean and bivalves ...
Abreu, Adlard, Alvarez-Pellitero, Alves, Aravindan, Bayne, Becker, Bo, Bohne-Kjersem, Brown, Buchmann, Buchmann, Buscaino, Chen, Clauss, Cobb, Colorni, Colorni, Concha, Concha, Concha, Corrales, Coulombe, Cox, Cruz-Lacierda, Ellis, FAO, FAO, FAO, FOESA, Geay, Gracey, Guardiola, Guerra-Santos, Harvell, Henry, Hirayama, Ibarz, Isani, Johnston, Joyce, Karlson, Karvonen, Kuperman, Lafferty, Landsberg, Lauckner, Lawler, Llewellyn, Loot, Macnab, Magnadottir, Marcogliese, Marcos-López, Martyniuk, Mladineo, Mohapatra, Molle, Murray, Noga, Noga, Noga, Noga, Noga, Ortuño, Panzenbock, Paoli, Paperna, Peng, Percin, R Core Team, Rajan, Rio-Zaragoza, Rio-Zaragoza, Rodrigues, Rodriguez-Tovar, Rogel, Sarropoulou, Saurabh, Shinn, Silva, Silva, Sitjà-Bobadilla, Smith, Smith, Smith, Soares, Soares, Tolosano, Tort, Tort, Ulevitch, Vidal-Martínez, Villarroel, Woo, Woo, Wu, Xie   +97 more
core   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Analysis of Toxoplasma gondii antigens with sera from toxoplasmosis patients

Revista da Sociedade Brasileira de Medicina Tropical, 1998
Some proteins of the Toxoplasma gondii are recognized by IgG, IgM and IgA antibodies in patients with acute and chronic toxoplasmosis, depending on the strain and stage of the Toxoplasma.
Maria de la Luz Galván-Ramírez, Cecilia Guillén-Vargas, Rafael Saavedra-Durán, Alfonso Islas-Rodríguez   +3 more
doaj  

Disturbance of oxidant/antioxidant balance, acute phase response and high mobility group box–1 protein in acute undifferentiated diarrhea in crossbred piglets

Indian Journal of Animal Sciences, 2014
The objective of the present study was to investigate the status of high mobility group box–1 (HMGB1) protein, oxidative stress and acute phase proteins in natural cases of acute undifferentiated diarrhoea in piglets aged 1–15 days old.
U K DE, REENA MUKHERJEE, S NANDI, BHARAT BHUSHAN, U DIMRI, A K VERMA   +5 more
doaj   +1 more source

Acute Phase Proteins as Cancer Biomarkers [PDF]

, 2011
Interactions between tumor cells and the host microenvironment have been shown to play a significant role in the initiation, progression, and invasiveness of human cancer. The complex changes in the tumor microenvironment have been shown to modulate the activation of the different arms of the host immune system including the acute phase response. Acute
Linda H. Malkas, W. Shannon Orr, Robert J. Hickey, John A. Sandoval   +3 more
openaire   +3 more sources

Nanocrystalline diamond film for biosensor applications [PDF]

, 2010
In this study, we have developed a novel capacitive biosensor based oil interdigitated gold nanodiamond (GID-NCD) electrode for detection of C-reactive protein (CRP) antigen.
Davidson, Jımmy L., Davidson, Jimmy L., Gurbuz, Yasar, Gürbüz, Yaşar, Howell, Mick, Kang, Weng P., Qureshi, Anjum   +6 more
core   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Characterization of Acute-Phase Proteins (Apps) [PDF]

, 2012
Upon Injury, a complex biological response of tissues is initiated to protect the organism and remove the injurious stimuli then trigger the healing process. Inflammation is a part of this complex response. The local response to tissue injury or infection is acute inflammation. Without inflammation, wounds and infections would never heal. This response
Ying Chu Lee, Sin Tak Chu
openaire   +3 more sources