Results 111 to 120 of about 975,400 (335)

Common promoter variant in cyclooxygenase-2 represses gene expression: evidence of role in acute-phase inflammatory response [PDF]

, 2002
Objective: Cyclooxygenase (COX)-2 is a key regulatory enzyme in the synthesis of prostanoids associated with trauma and inflammation. We investigated the COX-2 gene for functional variants that may influence susceptibility to disease.
Brull, D.J., Hill, M.R., Humphries, S.E., Laurent, G.J., Marshall, R.P., McAnulty, R.J., Papafili, A.   +6 more
core   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Impact of Diet Supplemented by Coconut Milk on Corticosterone and Acute Phase Protein Level under High Stocking Density

İstanbul Üniversitesi Veteriner Fakültesi Dergisi, 2016
The purpose of this study was to investigate effects of coconut milk supplementation on corticosterone and acute phase protein level under high stocking density.
Majid SHAKERI, Ehsan OSKOUEIAN, Pardis NAJAFI   +2 more
doaj   +1 more source

STUDIES OF ACUTE-PHASE PROTEIN. II. LOCALIZATION OF Cx-REACTIVE PROTEIN IN HEART IN INDUCED MYOCARDIAL INFARCTION IN RABBITS* [PDF]

, 1963
Irving Kushner, Louis Rakita, Melvin H. Kaplan   +2 more
openalex   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

The effects of feeding α-amylase-enhanced corn silage with different dietary starch concentrations to lactating dairy cows on milk production, nutrient digestibility, and blood metabolites

Journal of Dairy Science, 2023
: Corn silage is one of the most common ingredients fed to dairy cattle. Advancement of corn silage genetics has improved nutrient digestibility and dairy cow lactation performance in the past.
K.C. Krogstad, B.J. Bradford
doaj  

Evaluation of acute phase protein indexes in dogs with leishmaniasis at diagnosis, during and after short-term treatment

Veterinární Medicína, 2005
An acute phase index based on a combination of acute phase proteins which permitted monitoring the response to therapy of canine leishmaniasis was developed and evaluated in this study. Six dogs naturally infected by Leishmania infantum were treated with
S. Martinez-Subiela, J.J. Ceron
doaj   +1 more source

The Immunologic Properties and Identity of Mucopolysaccharides Associated with C-Reactive Protein in Acute Phase Human Serum [PDF]

, 1967
Y. Hokama, Monroe Coleman, Richard F. Riley   +2 more
openalex   +1 more source

Acute phase proteins in psoriasis

Collegium antropologicum, 2009
Psoriasis is a chronic, relapsing, inflammatory and hyperproliferative skin disorder. The levels of acute phase proteins are suggested to be elevated in those patients with acute disease. The expression of selected acute phase proteins as the parameters of humoral immunity has been analyzed in 70 patients with acute psoriasis and 40 healthy controls ...
Kostović, Krešimir, Šitum, Mirna, Batinac, Tanja, Biljan, Darko, Matišić, Danica   +4 more
openaire   +2 more sources

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source