Results 141 to 150 of about 1,143,701 (338)

Long-term interleukin-6 administration stimulates sustained thrombopoiesis and acute-phase protein synthesis in a small primate-- the marmoset [PDF]

, 1994
B. Ryffel, BD Car, Gaëtane Woerly, Markus Weber, F DiPadova, Michael Kammüller, Stephan Klug, Reinhard Neubert, Diether Neubert   +8 more
openalex   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Effects of lowering dietary protein content without or with increased protein-bound and feed-grade amino acids supply on growth performance, body composition, metabolism, and acute-phase protein of finishing pigs under daily cyclic heat stress. [PDF]

J Anim Sci, 2023
José Karpeggiane de Oliveira M, Diego Brandão Melo A, Alves Marçal D, Alves da Cunha Valini G, Alisson Silva C, Mari Veira A, Zem Fraga A, Righetti Arnaut P, Henrique Reis Furtado Campos P, Sousa Dos Santos L, Khun Kyaw Htoo J, Gastmann Brand H, Hauschild L.   +12 more
europepmc   +1 more source

Regulation of Net Biosynthesis of Serum Albumin and Acute Phase Plasma Proteins

, 1969
David W. John, Leon L. Miller
openalex   +1 more source

Effects of human recombinant interleukin-1β on protein synthesis in rat tissues compared with a classical acute-phase reaction induced by turpentine. Rapid response of muscle to interleukin-1β [PDF]

, 1991
Peter E. Ballmer, M.A. McNurlan, B G Southorn, I. S. Grant, P.J. Garlick   +4 more
openalex   +1 more source

The Acute-Phase Protein PTX3 is an Essential Mediator of Glial Scar Formation and Resolution of Brain Edema after Ischemic Injury

Journal of Cerebral Blood Flow and Metabolism, 2014
B. Rodriguez-Grande, Matimba Swana, Loan Nguyen, Pavlos C. Englezou, S. Maysami, S. Allan, N. Rothwell, C. Garlanda, Á. Dénes, E. Pinteaux   +9 more
semanticscholar   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Limits of Detection in Acute-Phase Protein Biomarkers Affect Inflammation Correction of Serum Ferritin for Quantifying Iron Status among School-Age and Preschool-Age Children and Reproductive-Age Women. [PDF]

J Nutr, 2022
Gosdin L, Sharma AJ, Suchdev PS, Jefferds ME, Young MF, Addo OY.   +5 more
europepmc   +1 more source

Expression of the gene encoding α₁‐acid glycoprotein in rabbit liver under acute‐phase conditions involves induction and activation of β and δ CCAAT‐enhancer‐binding proteins [PDF]

, 1994
Bimal K. Ray, Alpana Ray
openalex   +1 more source