Results 151 to 160 of about 1,088,024 (346)

The Biological Context of C-Reactive Protein as a Prognostic Marker in Renal Cell Carcinoma: Studies on the Acute Phase Cytokine Profile [PDF]

, 2020
Helene Hersvik Aarstad, Gigja Guðbrandsdottir, Karin M. Hjelle, Leif Bostad, Øystein Bruserud, Tor Henrik Anderson Tvedt, Christian Beisland   +6 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Profiling Tryptophan Catabolites of Human Gut Microbiota and Acute-Phase Protein Levels in Neonatal Dried Blood Specimens. [PDF]

Front Microbiol, 2021
Aust AC, Benesova E, Vidova V, Coufalikova K, Smetanova S, Borek I, Janku P, Budinska E, Klanova J, Thon V, Spacil Z.   +10 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Impact of levels of parasitemia and antibodies, acute-phase proteins, as well as stays abroad on hematological and biochemical parameters in 342 dogs with acute Babesia canis infection [PDF]

Imke M. von Hohnhorst, Andreas Moritz, C Eisenecker, Christina Strübe, Kezia Eudora Rodjana, Elisabeth Müller, Ingo Schäfer   +6 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

PECULARITIES OF COMPOSITION OF PROTEIN FRACTIONS AND ACUTE-PHASE LIQUOR PROTEINS IN NORM AND AT COMPRESSION SYNDROME OF LUMBAR REGION OF SPINE

Acta Biomedica Scientifica, 2012
Peculiarities of composition of protein fractions and acute-phase liquor proteins as the indications of activity of immunologic liquor reactions were studied by biochemical method in 15 patients without neurological diseases and.
P. G. Gruzin, V. A. Sorokovikov
doaj  

Oxidized Low Density Lipoprotein and High Sensitive C-Reactive Protein in Non-Diabetic, Pre-Diabetic and Diabetic Patients in the Acute Phase of the First Myocardial Infarction Treated by Primary Percutaneous Coronary Intervention / Oksidovani Lipoprotein Niske Gustine I Visokosenzitivni C-Reaktivni Protein Kod Nedijabetičara, Predijabetičara I Dijabetičara U Akutnoj Fazi Prvog Infarkta Miokarda Lečenog Primarnom Perkutanom Koronarnom Intervencijom [PDF]

, 2014
Danijela Trifunović, Sanja Stanković, Jelena Marinković, Marko Banović, Nina Đukanović, Olga Vasović, Bosiljka Vujisić-Tešić, M Petrović, Jelena Stepanović, Ana Đorđević-Dikić, Branko Beleslin, Ivana Nedeljković, Milorad Tešić, Miodrag Ostojić   +13 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

High concentrate-induced subacute ruminal acidosis (SARA) increases plasma acute phase proteins (APPs) and cortisol in goats

, 2014
Yimin Jia, S.Q. Wang, Yingdong Ni, Yanfeng Zhang, Su Zhuang, Xiangzhen Shen   +5 more
openalex   +1 more source