Results 31 to 40 of about 950,229 (336)

Newly synthesized mRNA escapes translational repression during the acute phase of the mammalian unfolded protein response.

PLoS ONE, 2022
Endoplasmic Reticulum (ER) stress, caused by the accumulation of misfolded proteins in the ER, elicits a homeostatic mechanism known as the Unfolded Protein Response (UPR).
Mohammed R Alzahrani, Bo-Jhih Guan, Leah L Zagore, Jing Wu, Chien-Wen Chen, Donny D Licatalosi, Kristian E Baker, Maria Hatzoglou   +7 more
doaj   +1 more source

Binding of bromocresol green and bromocresol purple to albumin in hemodialysis patients [PDF]

, 2017
BACKGROUND: Colorimetric albumin assays based on binding to bromocresol purple (BCP) and bromocresol green (BCG) yield different results in chronic kidney disease. Altered dye binding of carbamylated albumin has been suggested as a cause.
Delanghe, Joris, Delanghe, Sigurd, Eloot, Sunny, Glorieux, Griet, Pletinck, Anneleen, Schepers, Eva, Speeckaert, Marijn, Van Biesen, Wim, Van de Velde, Nadeige   +8 more
core   +1 more source

Serum Amyloid A Stimulates Vascular and Renal Dysfunction in Apolipoprotein E-Deficient Mice Fed a Normal Chow Diet

Frontiers in Immunology, 2019
Elevated serum amyloid A (SAA) levels may promote endothelial dysfunction, which is linked to cardiovascular and renal pathologies. We investigated the effect of SAA on vascular and renal function in apolipoprotein E-deficient (ApoE−/−) mice. Male ApoE−/−
Belal Chami, Farjaneh Hossain, Thomas W. Hambly, Xiaoping Cai, Roshanak Aran, Genevieve Fong, Abigail Vellajo, Nathan J.J Martin, XiaoSuo Wang, Joanne M. Dennis, Arpeeta Sharma, Waled A. Shihata, Waled A. Shihata, Waled A. Shihata, Jaye P. F. Chin-Dusting, Jaye P. F. Chin-Dusting, Jaye P. F. Chin-Dusting, Judy B. de Haan, Alexandra Sharland, Carolyn L. Geczy, Ben Freedman, Paul K. Witting   +21 more
doaj   +1 more source

Changes in the Serum Protein Electrophoresis Profile in Dogs With Pyometra

Frontiers in Veterinary Science, 2021
Serum proteins are involved in the regulation of inflammation, and therefore, serum protein profiling provides important insights in diverse inflammatory reactions.
Ji-Seon Yoon, DoHyeon Yu, Jinho Park
doaj   +1 more source

Recombinant human interleukin-6 (IL-6/BSF-2/HSF) regulates the synthesis of acute phase proteins in human hepatocytes [PDF]

, 1988
Recombinant human IL-6 (rhIL-6) is a potent inducer of the synthesis of acute phase proteins in adult human hepatocytes. A wide spectrum of acute phase proteins is regulated by this mediator.
Castell, José V., David, Martina, Gómez-Lechón, Maria J., Heinrich, Peter C., Hirano, Toshio, Kishimoto, Tadamitsu   +5 more
core   +1 more source

Inflammatory Measures in Depressed Patients With and Without a History of Adverse Childhood Experiences

Frontiers in Psychiatry, 2018
Background: Major depressive disorder (MDD) is a complex psychiatric condition with different subtypes and etiologies. Exposure to adverse childhood experiences (ACE) is an important risk factor for the development of MDD later in life. Evidence suggests
Karin de Punder, Sonja Entringer, Sonja Entringer, Sonja Entringer, Christine Heim, Christine Heim, Christian E. Deuter, Christian Otte, Katja Wingenfeld, Linn K. Kuehl   +9 more
doaj   +1 more source

Estimation of YKL-40 levels in serum and gingival crevicular fluid in chronic periodontitis and type 2 diabetes patients among South Indian population: A clinical study

Contemporary Clinical Dentistry, 2019
Background: YKL-40 is a novel potential inflammatory marker in relation to both acute and chronic inflammation. It is secreted by activated neutrophils and macrophages in acute or chronic inflammation. It strongly binds to chitin and heparin.
Prathush Ajit Kumar, Krishna Kripal, Kavita Chandrasekaran, Sushma Reddy Bhavanam   +3 more
doaj   +1 more source

Evaluation of thrombomodulin and pentraxin-3 as diagnostic biomarkers in calves with sepsis

Veterinární Medicína, 2018
Early diagnosis and treatment of sepsis in patients are crucial for their survival and can help reduce mortality rates. Novel biomarkers, such as thrombomodulin and pentraxin-3, have been used as diagnostic, prognostic and mortality indicators in ...
O. Aygun, R. Yildiz
doaj   +1 more source

The Role of Chloroquine Phosphate on Acute Phase Reactant Proteins in Patients with Knee Osteoarthritis

Iraqi Journal of Pharmaceutical Sciences, 2017
The acute phase response is a major pathophysiologic phenomenon that accompanies inflammation whether acute or chronic. Complement (C3 and C4) and C - reactive protein (CRP) are positive acute phase proteins (+ ve APPs ).
Eman S. Saleh, Kismet M.Turki, Mohammed H.Al-Osami   +2 more
doaj   +3 more sources

Functional protection by acute phase proteins alpha(1)-acid glycoprotein and alpha(1)-antitrypsin against ischemia/reperfusion injury by preventing apoptosis and inflammation. [PDF]

, 2000
BACKGROUND: Ischemia followed by reperfusion (I/R) causes apoptosis, inflammation, and tissue damage leading to organ malfunction. Ischemic preconditioning can protect against such injury.
BUURMAN, WA, DAEMEN, M, Denecker, Geertrui, HEEMSKERK, VH, VAN 'T VEER, C, Vandenabeele, Peter, WOLFS, TGAM   +6 more
core   +3 more sources