Interleukin-6 is the major regulator of acute phase protein synthesis in adult human hepatocytes [PDF]
The three monokines interleukin-1β (IL-1β), tumor necrosis factor α (TNFα), and interleukin-6 (IL-6) modulate acute phase plasma protein synthesis in adult human hepatocytes. Only IL-6 stimulates the synthesis of the full spectrum of acute phase proteins
Andus, Tilo+7 more
core +1 more source
The complementary role of histology and proteomics for diagnosis and typing of systemic amyloidosis
The tissue diagnosis of amyloidosis and confirmation of fibril protein type, which are crucial for clinical management, have traditionally relied on Congo red (CR) staining followed by immunohistochemistry (IHC) using fibril protein specific antibodies ...
Tamer Rezk+12 more
doaj +1 more source
STAT3 Activation in Skeletal Muscle Links Muscle Wasting and the Acute Phase Response in Cancer Cachexia [PDF]
Cachexia, or weight loss despite adequate nutrition, significantly impairs quality of life and response to therapy in cancer patients. In cancer patients, skeletal muscle wasting, weight loss and mortality are all positively associated with increased ...
AC McPherron+89 more
core +6 more sources
Binding of bromocresol green and bromocresol purple to albumin in hemodialysis patients [PDF]
BACKGROUND: Colorimetric albumin assays based on binding to bromocresol purple (BCP) and bromocresol green (BCG) yield different results in chronic kidney disease. Altered dye binding of carbamylated albumin has been suggested as a cause.
Delanghe, Joris+8 more
core +1 more source
Changes in Acute-Phase Proteins in Plasma during the Periparturient Period of Dairy Goats. [PDF]
The present study was conducted regarding four acute-phase proteins (APPs) including C-reactive protein (CRP), ceruloplasmin (CP), serum amyloid A (SAA), and haptoglobin (HP) in dairy goats during the periparturient period.
Zeng F+9 more
europepmc +2 more sources
Blood fibrinogen concentrations in New Zealand White rabbits during the first year of life [PDF]
The aim of this study was to examine the reference range of blood plasma fibrinogen, which belongs to the group of moderate acute phase protein in rabbits. The experiment followed the dynamics of blood plasma fibrinogen (Fb) during the first year of life
Y. Petrova+3 more
doaj +1 more source
Recombinant human interleukin-6 (IL-6/BSF-2/HSF) regulates the synthesis of acute phase proteins in human hepatocytes [PDF]
Recombinant human IL-6 (rhIL-6) is a potent inducer of the synthesis of acute phase proteins in adult human hepatocytes. A wide spectrum of acute phase proteins is regulated by this mediator.
Castell, José V.+5 more
core +1 more source
Acute phase response in experimentally infected broilers with avian infectious bronchitis virus serotype 4/91 [PDF]
Measurement of acute phase proteins is important for diagnosis of animal diseases. In the present study, effects of avian infectious bronchitis virus infection on acute phase response and acute phase proteins were determined.
ABSALAN FARD, K.+2 more
core +2 more sources
Virtual Identification of Essential Proteins Within the Protein Interaction Network of Yeast [PDF]
Topological analysis of large scale protein-protein interaction networks (PINs) is important for understanding the organisational and functional principles of individual proteins. The number of interactions that a protein has in a PIN has been observed to be correlated with its indispensability.
arxiv +1 more source
Differences in GlycA and lipoprotein particle parameters may help distinguish acute kawasaki disease from other febrile illnesses in children. [PDF]
BackgroundGlycosylation patterns of serum proteins, such as α1-acid glycoprotein, are modified during an acute phase reaction. The response of acute Kawasaki disease (KD) patients to IVIG treatment has been linked to sialic acid levels on native IgG ...
Burns, Jane C+8 more
core +3 more sources