Results 101 to 110 of about 7,542,962 (284)

Pediatric acute disseminated encephalomyelitis following asymptomatic coronavirus disease 2019

open access: yesIDCases
After the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic emerged, the virus spread rapidly worldwide, and outbreaks continued to occur intermittently.
Yuta Nakamura   +3 more
doaj   +1 more source

Acute and specialist health services more than a hospital, a strategic plan 1998-2006, final report

open access: yes, 1998
The purpose of this report is to articulate an appropriate mix of services for Acute and Specialist Health Care in the Northern Territory. It represents the outcome from consultation with over 500 interested stakeholders throughout the Northern Territory
Acute and Specialist Care Branch
core  

Estimated glomerular filtration rate correlates poorly with four-hour creatinine clearance in critically ill patients with acute kidney injury. [PDF]

open access: yes, 2013
Introduction. RIFLE and AKIN provide a standardised classification of acute kidney injury (AKI), but their categorical rather than continuous nature restricts their use to a research tool. A more accurate real-time description of renal function in AKI is
Iain A. M. MacPhee   +5 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Nuclear matrix-associated poly(adpribosyl)ation system in rat hepatocytes during the acute phase reaction [PDF]

open access: yesArchives of Biological Sciences, 2003
Vidaković Melita   +2 more
doaj   +1 more source

Acute hospitals divison: operational plan 2014 [PDF]

open access: yes, 2014
The implementation of the Government’s decision to re-organise the acute hospitals system will be guided by the Department of Health’s Future Health – A Strategic Framework for Reform of the Health Service 2012-2015. The Health Service strategic reform
Health Service Executive (HSE), Acute Hospitals Division
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Antioxidant status and acute phase reactants in pregnant women infected with Plasmodium falciparum

open access: yesRwanda Medical Journal
INTRODUCTION: Malaria during pregnancy remains a public health issue. The most deadly plasmodium, Plasmodium falciparum, kills about 40% of the world's population, especially pregnant women and children under five.
D. Atere Adedeji   +3 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Common promoter variant in cyclooxygenase-2 represses gene expression: evidence of role in acute-phase inflammatory response [PDF]

open access: yes, 2002
Objective: Cyclooxygenase (COX)-2 is a key regulatory enzyme in the synthesis of prostanoids associated with trauma and inflammation. We investigated the COX-2 gene for functional variants that may influence susceptibility to disease.
Humphries, S.E.   +6 more
core  

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