Results 81 to 90 of about 7,542,962 (284)

Reaction time and intelligence:Comparing associations based on two response modes [PDF]

, 2013
People who score highly on intelligence tests also tend to have faster and less variable reaction times. Effect size estimates for the reaction time-intelligence association are larger in samples that are more representative of the population.
Deary, Ian J., Liewald, David, Nissan, Jack   +2 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Optimal combinations of acute phase proteins for detecting infectious disease in pigs [PDF]

, 2011
Peer ...
Mathilda JM Toussaint, Eckersall, P.D., Anders Stockmarr, Campbell, Fiona M, Rakel Carpintero, Piñeiro, M., Toussaint, Mathilda J.M., Sorensen, N., Eckersall, P. David, Campbell, F.M., Nanna Sorensen, Campbell, Fiona Margaret, Toussaint, M.J.M., Carpintero, Rakel, Fiona M Campbell, Lampreave, F., Skall Sorensen, Nanna, P Eckersall, Carpintero, R., Erik Gruys, Piñeiro, Matilde, Heegaard, P.M.H., Fermin Lampreave, Stockmarr, A., Toussaint, Mathilda JM, Lampreave, Fermin, Sørensen, Nanna Skall, Matilde Piñeiro, Heegaard, Peter M. H., Peter MH Heegaard, Gruys, Erik, Gruys, E., Eckersall, P David, Stockmarr, Anders, Lampreave Fermin, Eckersall P, Stockmarr Anders, Sorensen Nanna, Gruys Erik, Carpintero Rakel, Heegaard Peter MH, Campbell Fiona M, Piñeiro Matilde, Toussaint Mathilda JM   +43 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Bis(trifluoromethyl)methylene addition to vinyl-terminated SAMs : a gas-phase C–C bond-forming reaction on a surface [PDF]

, 2014
The authors acknowledge the Scottish Funding Council for a SPIRIT Studentship (M.A.) and the EPSRC (EP/K000411/1) for financial support, and D.O’H. acknowledges the European Research Council for an Advanced Grant and the Royal Society for a Wolfson ...
Hähner, Georg, David O’Hagan, Malgorzata Adamkiewicz, Georg Hähner (1319703), Georg Hähner, O'Hagan, David, Malgorzata Adamkiewicz (1319706), David O’Hagan (1313640), Adamkiewicz, Malgorzata   +8 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

The PML-RAR alpha transcript in long-term follow-up of acute promyelocytic leukemia patients [PDF]

, 2001
Background and Objectives. Detection of PML-RAR alpha transcripts by RT-PCR is now established as a rapid and sensitive method for diagnosis of acute promyelocytic leukemia (APL), Although the majority of patients in longterm clinical remission are ...
Gameiro, P, Diamond, J, Foroni, L, Silva, AL, Mehta, AB, Prentice, HG, Carrara, P, Vieira, S, Guimaraes, JE, Parreira, A, Hoffbrand, AV, de Sousa, AB   +11 more
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Whole blood viscosity assessment issues IV: Prevalence in acute phase inflammation

, 2010
Background: Hyperviscosity syndrome has been suggested as not simply an acute reaction. Yet, erythrocyte sedimentation rate is associated with whole blood viscosity and it is an indirect acute phase inflammation marker.
Nwose, Ezekiel Uba
core   +1 more source

The acute phase protein response to intramammary infection in water buffalo (Bubalus bubalis)

, 2010
Acute phase proteins are a group of serum proteins that change their concentration in animals following infection, inflammation or stress. Serum amyloid A (SAA) and α1-acid glycoprotein (AGP) are regarded as acute phase proteins in bovine, and their ...
P. Sartorelli, L.F. Pisani, L.M. Scaccabarozzi, C. Lecchi, P. Moroni, M.M. Rahman, F. Ceciliani, P. D. Eckersall   +7 more
core   +2 more sources