Results 81 to 90 of about 1,149,987 (297)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

A multimodal approach to ameliorate acute phase reaction induced by zoledronic acid

Osteoporosis and Sarcopenia, 2023
Chung-Hwan Chen, Sung-Yen Lin, Tien-Ching Lee, Cheng-Jung Ho, Jhong-You Li   +4 more
doaj   +1 more source

Orientia tsutsugamushi in Eschars from Scrub Typhus Patients

Emerging Infectious Diseases, 2006
To verify the value of eschars for the diagnosis of scrub typhus and to characterize genotypes of Orientia tsutsugamushi in patients, we examined eschars and blood specimens of 7 patients from Shandong Province, People's Republic of China, for O ...
Yun-Xi Liu, Wu-Chun Cao, Yuan Gao, Jing-Lan Zhang, Zhan-Qing Yang, Zhong-Tang Zhao, Janet Foley   +6 more
doaj   +1 more source

Acute Phase Reaction and Fracture Risk Reduction: Are Gamma-Delta T Cells and Hypovitaminosis D the Missing Link? [PDF]

J Bone Miner Res, 2022
Adami G, Fassio A, Gatti D, Viapiana O, Rossini M.   +4 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Luteinizing Hormone and Testosterone Levels during Acute Phase of Severe Traumatic Brain Injury: Prognostic Implications for Adult Male Patients

Frontiers in Endocrinology, 2018
Traumatic brain injury (TBI) is a worldwide core public health problem affecting mostly young male subjects. An alarming increase in incidence has turned TBI into a leading cause of morbidity and mortality in young adults as well as a tremendous resource
Alexandre Hohl, Alexandre Hohl, Fernando Areas Zanela, Gabriela Ghisi, Marcelo Fernando Ronsoni, Marcelo Fernando Ronsoni, Alexandre Paim Diaz, Alexandre Paim Diaz, Marcelo Liborio Schwarzbold, Marcelo Liborio Schwarzbold, Alcir Luiz Dafre, Alcir Luiz Dafre, Benjamin Reddi, Benjamin Reddi, Kátia Lin, Kátia Lin, Felipe Dal Pizzol, Felipe Dal Pizzol, Roger Walz, Roger Walz   +19 more
doaj   +1 more source

Age-Related Changes in Acute Phase Reaction, Cortisol, and Haematological Parameters in Ewes in the Periparturient Period. [PDF]

Animals (Basel), 2021
Greguła-Kania M, Kosior-Korzecka U, Hahaj-Siembida A, Kania K, Szysiak N, Junkuszew A.   +5 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Systemic cytokines related to memory function 6–9 months and 12–15 months after SARS-CoV-2 infection

Scientific Reports
Cognitive symptoms persisting beyond the acute phase of COVID-19 infection are commonly described for up to 2 years after infection. The relationship between cognitive performance, in particular episodic memory processes observed chronically after ...
A. Nuber-Champier, G. Breville, P. Voruz, I. Jacot de Alcântara, A. Cionca, G. Allali, P. H. Lalive, L. Benzakour, K.-O. Lövblad, O. Braillard, M. Nehme, M. Coen, J. Serratrice, J.-L. Reny, J. Pugin, I. Guessous, B. N. Landis, F. Assal, Julie Anne Péron   +18 more
doaj   +1 more source